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Neuro-ophthalmic manifestations of Ehlers-Danlos syndrome
Sruti S Rachapudi1, Noor A Laylani2, Pamela A Davila-Siliezar2
1University of Texas Medical Branch, Galveston.
Purpose Of Review:
To review the neuro-ophthalmic manifestations of Ehlers-Danlos syndrome (EDS).
Recent Findings:
Ehlers-Danlos syndrome (EDS) is a rare genetic disorder with an estimated prevalence of 1 in 5000 individuals, but its true prevalence may be underestimated because of variable clinical presentations and limited awareness among healthcare professionals. The neuro-ophthalmic features of EDS may be difficult to recognize in context but new molecular genetic testing is now available for identification of specific subtypes of EDS.
Summary:
Ophthalmic manifestations of EDS include loss of vision and double vision (strabismus), high myopia, retinal detachment, and blue sclera. The vascular subtype of EDS can present as a carotid-cavernous fistula, intracranial aneurysm, or arterial dissection.
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