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Preparation and Reactions of Sulfides02:26

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Sulfides are the sulfur analog of ethers, just as thiols are the sulfur analog of alcohol. Like ethers, sulfides also consist of two hydrocarbon groups bonded to the central sulfur atom. Depending upon the type of groups present, sulfides can be symmetrical or asymmetrical. Symmetrical sulfides can be prepared via an SN2 reaction between 2 equivalents of an alkyl halide and one equivalent of sodium sulfide.
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SBAR is an effective communication tool used by healthcare professionals to communicate patient information accurately. SBAR stands for Situation, Background, Assessment, and Recommendation. For a better understanding, an example is given below.
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Thiols and sulfides are sulfur analogs of alcohols and ethers, respectively, where the sulfur atom takes the place of the oxygen atom. Thus, thiols are generally represented as RSH, where R is an alkyl substituent and —SH is the functional group. On the other hand, in sulfides, the central sulfur atom is bonded to two hydrocarbon groups on either side. Depending upon the type of group, sulfides can be either symmetrical or asymmetrical. Both thiols and sulfides display a bent geometry,...
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Sulfonation of benzene is a reaction wherein benzene is treated with fuming sulfuric acid at room temperature to produce benzenesulfonic acid. Fuming sulfuric acid is a mixture of sulfur trioxide and concentrated sulfuric acid.
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Updated: Jul 16, 2025

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MakeSBML: A tool for converting between Antimony and SBML.

Bartholomew E Jardine1, Lucian P Smith1, Herbert M Sauro1

  • 1Bioengineering, University of Washington, Box 355061, Seattle, 98195, WA, United States.

Arxiv
|September 21, 2023
PubMed
Summary
This summary is machine-generated.

MakeSBML is a free, web-based tool for creating and editing System Biology Markup Language (SBML) models using the human-readable Antimony language. This installation-free application simplifies systems biology research by enhancing model accessibility and reproducibility.

Keywords:
AntimonySBMLSoftwareSystems biologymodelingreaction networks

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Area of Science:

  • Systems Biology
  • Computational Biology
  • Bioinformatics

Background:

  • System Biology Markup Language (SBML) is crucial for describing biochemical networks but is computer-readable, not human-readable.
  • Creating and editing SBML models can be challenging due to its complexity.
  • Reproducibility of systems biology models is essential for scientific advancement.

Approach:

  • Developed MakeSBML, a client-based web application for seamless SBML model creation and editing.
  • Implemented translation between human-readable Antimony and SBML formats.
  • Hosted on GitHub for easy accessibility and minimal maintenance, requiring no user installation.

Key Points:

  • MakeSBML facilitates the creation, editing, and searching of SBML models.
  • The tool supports bidirectional translation between Antimony and SBML.
  • Client-based web design ensures no installation is required, simplifying user access.
  • Deployment on GitHub reduces maintenance costs and allows for easy relocation.

Conclusions:

  • MakeSBML enhances the usability of SBML models in systems biology research.
  • The tool promotes easier model creation, editing, and sharing.
  • By bridging the gap between human-readable and computer-readable formats, MakeSBML improves model accessibility and reproducibility.