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Recent Progress on Chiral Carbon Dots: Synthetic Strategies and Biomedical Applications
Xueli Chen1, Meizhe Yu1, Peili Li2
1School of Chemistry and Chemical Engineering, Nanjing University of Science and Technology, Nanjing 210094, China.
ACS Biomaterials Science & Engineering
|September 22, 2023
Summary
Chiral carbon dots (Ch-CDs) offer unique chiral optical properties and biomedical advantages. This review comprehensively covers their precursors, preparation, and diverse biomedical applications, guiding future research.
Area of Science:
- Materials Science
- Nanotechnology
- Biomedical Engineering
Background:
- Chiral carbon dots (Ch-CDs) are emerging nanomaterials with inherent chirality.
- They possess excellent chemical stability, biocompatibility, and therapeutic properties.
- Existing reviews lack a comprehensive overview of Ch-CDs' precursor selection, synthesis, and biomedical applications.
Purpose of the Study:
- To provide the first comprehensive review on chiral carbon dots (Ch-CDs).
- To summarize precursor selection and preparation methods for Ch-CDs.
- To detail Ch-CDs' applications in biosensing, bioimaging, drug delivery, and more.
Main Methods:
- Literature review of recent reports on Ch-CDs.
- Categorization of precursor materials and synthesis techniques.
- Analysis of Ch-CDs' performance in various biomedical applications.
Main Results:
- Ch-CDs retain precursor chirality, exhibiting unique optical properties.
- Diverse applications include biosensing, bioimaging, drug delivery, and antibacterial therapies.
- Key preparation methods and precursor choices are identified.
Conclusions:
- Ch-CDs show significant promise for biomedical engineering applications.
- Further research is needed to overcome challenges and optimize Ch-CDs.
- This review offers guidance for developing novel Ch-CDs and advancing their clinical translation.
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