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Updated: Jul 16, 2025

Establishment of Rat Models Mimicking Gender-affirming Hormone Therapies
Published on: January 10, 2025
Gender-Affirming Medical Treatments
1Pediatric Endocrinology Division, UT Southwestern Medical Center, 5323 Harry Hines Boulevard, Dallas, TX 75390, USA.
This article outlines the role of medical providers in gender-affirming care for transgender and gender diverse youth. It emphasizes a multidisciplinary approach for safe and effective medical treatments, aligning with expert recommendations.
Area of Science:
- Pediatric Endocrinology
- Adolescent Medicine
- Gender Studies
Background:
- Gender dysphoria involves incongruence between assigned sex and experienced gender, causing distress.
- Transgender and gender diverse minors require specialized care.
- Current guidelines recommend a multidisciplinary approach.
Purpose of the Study:
- To define the role of medical providers in gender-affirming care for youth.
- To highlight the importance of a multidisciplinary team.
- To ensure safe and effective medical interventions.
Main Methods:
- Review of Endocrine Society guidelines.
- Analysis of World Professional Association for Transgender Health (WPATH) Standards of Care 8th Edition.
- Outline of medical provider responsibilities.
Main Results:
- Medical providers are central to implementing gender-affirming treatments.
- Collaboration with mental health professionals is crucial.
- Adherence to established standards ensures optimal outcomes.
Conclusions:
- Medical providers play a vital role in supporting transgender and gender diverse youth.
- A comprehensive, multidisciplinary approach is essential for effective care.
- Safe and evidence-based medical treatments are key to improving well-being.
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