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Venous Thromboembolism Prophylaxis in Otolaryngologic Patients Using Caprini Assessment
Michael A Edwards1, Emily Brennan2, Amy L Rutt3
1Advanced GI and Bariatric Surgery Division, Department of Surgery, Mayo Clinic, Jacksonville, Florida, U.S.A.
Appropriate venous thromboembolism (VTE) prophylaxis in otolaryngology surgery reduces VTE events, but increases inpatient bleeding. Balancing VTE risk and bleeding is crucial for patient outcomes.
Area of Science:
- Otolaryngology
- Vascular Surgery
- Medical Guidelines
Background:
- Venous thromboembolism (VTE) is a significant risk in otolaryngology (ORL) surgery.
- The Caprini guideline provides a framework for VTE prophylaxis, but its utilization and impact in ORL patients require further investigation.
Purpose of the Study:
- To assess the utilization of Caprini guideline-indicated VTE prophylaxis in elective ORL surgeries.
- To evaluate the impact of this prophylaxis on VTE and bleeding outcomes in ORL patients.
Main Methods:
- Retrospective analysis of 4955 elective ORL surgeries from 2016-2021.
- Logistic regression models used to analyze associations between patient characteristics, prophylaxis, and VTE/bleeding events.
Main Results:
- Only 30% of inpatient and 2% of discharged ORL patients received appropriate VTE prophylaxis.
- Inappropriate prophylaxis was linked to a 3.5-fold increase in inpatient VTE and all pulmonary embolism (PE) events.
- Appropriate prophylaxis reduced inpatient VTE risk but was associated with higher inpatient bleeding; however, post-discharge bleeding occurred only in patients without prophylaxis.
Conclusions:
- Caprini VTE prophylaxis effectively reduces inpatient and post-discharge VTE in ORL surgery.
- The benefits of VTE prophylaxis must be weighed against the increased risk of inpatient postoperative bleeding.
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