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A High Resolution Method to Monitor Phosphorylation-dependent Activation of IRF3
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C-terminal variants in CDC42 drive type I interferon-dependent autoinflammation in NOCARH syndrome reversible by

Friedrich G Kapp1, Stefanie Kretschmer2, Cora C A Beckmann1

  • 1Division of Pediatric Hematology and Oncology, Department of Pediatric and Adolescent Medicine, University Medical Center Freiburg, University of Freiburg, Freiburg, Germany.

Clinical Immunology (Orlando, Fla.)
|September 23, 2023
PubMed

Keywords:
AutoinflammationCDC42JAK inhibitionNOCARHRuxolitinibType I interferonopathy

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