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Aseptic Meningitis after BNT-162b2 COVID-19 Vaccination: Case Report and Literature Review

Yuji Kato1, Takashi Osada1, Nobuo Araki2

  • 1Department of Neurology and Cerebrovascular Medicine, Saitama Medical University International Medical Center, Hidaka, Japan.

The Keio Journal of Medicine
|September 24, 2023
PubMed

Insights

Aseptic meningitis, a rare side effect, can occur after COVID-19 vaccination. Early diagnosis and treatment with methylprednisolone can resolve severe symptoms like headache and photophobia.

Area of Science:

  • Neurology
  • Immunology
  • Vaccinology

Background:

  • COVID-19 vaccines have been associated with various neurological side effects.
  • Aseptic meningitis is a rare but serious condition characterized by inflammation of the membranes surrounding the brain and spinal cord.

Conclusions:

  • Aseptic meningitis is an uncommon but potential adverse event following COVID-19 vaccination.
  • Persistent or delayed headache after vaccination warrants suspicion for aseptic meningitis.
  • Prompt diagnosis and corticosteroid therapy can lead to favorable outcomes.
Keywords:
adverse reactionaseptic meningitiscovid-19 vaccinesteroid

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