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A Single-cell and Spatial RNA-seq Database for Alzheimer's Disease (ssREAD)
Cankun Wang1, Diana Acosta2, Megan McNutt1
1Department of Biomedical Informatics, The Ohio State University, OH 43210, USA.
A new database, ssREAD, centralizes single-cell and spatial RNA sequencing data for Alzheimer's Disease (AD) research. It provides a vast resource and analytical tools to advance understanding of AD pathology at a cellular level.
Area of Science:
- Neuroscience
- Genomics
- Bioinformatics
Background:
- Alzheimer's Disease (AD) research increasingly utilizes single-cell and spatial transcriptomics.
- Existing data repositories lack comprehensiveness and user-friendliness for these complex datasets.
Conclusions:
- ssREAD serves as a valuable, user-friendly resource for Alzheimer's Disease research.
- The database and its analytical tools will accelerate discoveries in AD pathology.
- ssREAD promotes integrated analysis of multi-omic data in neurodegenerative disease research.
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