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Related Experiment Video

Updated: Jul 15, 2025

A Novel Method for Involving Women of Color at High Risk for Preterm Birth in Research Priority Setting
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Disparities in maternal mortality.

Phuong Tran1, Barbara Jreij2, Farideh Sistani1

  • 1Department of Practice, Sciences and Health Outcomes Research, University of Maryland School of Pharmacy, Baltimore, MD, USA.

Journal of Clinical and Translational Science
|September 25, 2023
PubMed
Summary

Maternal mortality in the USA is high, especially for Black women. Opioid use disorder worsens racial and age disparities in pregnancy outcomes, highlighting the need for targeted interventions and policy changes.

Keywords:
Maternal mortalityage disparitiesmiscarriagepublic healthracial disparities

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Area of Science:

  • Public Health
  • Maternal Health
  • Health Disparities

Background:

  • Maternal mortality rates in the USA remain high.
  • Persistent racial and socioeconomic disparities exist in maternal health outcomes.
  • Understanding contributing factors is crucial for improving care.

Purpose of the Study:

  • To identify factors associated with maternal death among hospital admissions for pregnant women in Maryland.
  • To examine racial and age discrepancies in gestational health outcomes.
  • To assess the exacerbating role of opioid use disorder in adverse pregnancy outcomes.

Main Methods:

  • Analysis of 207,016 hospital admissions for pregnant women in Maryland (2017-2019).
  • Logistic regression modeling to identify predictors of maternal death.
  • Examination of disparities based on race and age.

Main Results:

  • Black women faced a higher risk of maternal mortality compared to white women.
  • Significant racial and age discrepancies were observed in gestational health.
  • Opioid use disorder was found to exacerbate adverse pregnancy outcomes.

Conclusions:

  • Racial and age disparities significantly impact maternal mortality.
  • Opioid use disorder is a critical factor worsening these disparities.
  • Findings underscore the need for informed policy and resource allocation to address drivers of adverse pregnancy outcomes.