Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Evolution of Microbial Genome

Evolution of Microbial Genome

Microbial genome evolution is a highly dynamic process shaped by continual gene gain and loss across species and strains. This genomic flexibility allows microorganisms to adapt rapidly to environmental pressures and interactions with other organisms. Central to understanding this diversity is the distinction between the core and pan genomes.The core genome comprises the genes shared by all sampled strains of a species, representing essential functions needed for fundamental cellular processes.

Microenvironments

Microenvironments

Microorganisms inhabit highly localized spaces known as microenvironments, which are defined by distinct physical and chemical characteristics. These include oxygen concentration, pH, temperature, light availability, and nutrient levels. The conditions within a microenvironment can differ markedly from those in the surrounding area and significantly influence microbial growth, metabolism, and community structure.Microenvironments often display sharp physicochemical gradients over small spatial...

Malaria

Malaria

Malaria pathogenesis in humans reflects a delicate interplay between parasite biology and host response. Clinical illness reflects a host’s immune response to the parasite’s asexual replication cycle, which is often asymptomatic in individuals with partial immunity. From the parasite's perspective, transmission between mosquito and human with minimal host pathology is evolutionarily advantageous. Among the six Plasmodium species infecting humans, P. falciparum and P. vivax dominate in global...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Impact of Hypothyroidism on Short-Term and Long-Term Outcomes of Coronary Artery Bypass Graft Surgery.

Thyroid : official journal of the American Thyroid Association·2026

Same author

A humanized IFN-γ mouse model reveals skin eschar formation, enhanced susceptibility and scrub typhus pathogenesis.

PLoS pathogens·2026

Same author

Association between Vitamin B12 Levels and Colon Cancer Survival: A Global Network Study.

Cancer research communications·2026

Same author

Vertical transmission of mosquito microbiota and its effects on offspring development.

bioRxiv : the preprint server for biology·2025

Same author

Reconstructing the three-dimensional architecture of extrachromosomal DNA with ec3D.

Nature communications·2025

Same author

Erratum: EHRchitect: An open-source software tool for medical event sequences data extraction from Electronic Health Records - CORRIGENDUM.

Journal of clinical and translational science·2025

Same journal

Flubendazole 2.0: Designing a large field trial in dogs for a challenging setting.

PLoS neglected tropical diseases·2026

Same journal

Temporal and spatial patterns of Leprosy in Uganda, 2020-2024: A nationwide surveillance analysis.

PLoS neglected tropical diseases·2026

Same journal

Prevalence and risk factors of asymptomatic Plasmodium spp. infection in the military population of the Colombian National Army.

PLoS neglected tropical diseases·2026

Same journal

Mobility and non-household environments: Understanding dengue transmission patterns in urban contexts.

PLoS neglected tropical diseases·2026

Same journal

Hantavirus stability and inactivation.

PLoS neglected tropical diseases·2026

Same journal

Disability as a neglected outcome of neglected tropical diseases: A systematic review.

PLoS neglected tropical diseases·2026

See all related articles

Search research articles

Related Experiment Video

Updated: Jul 1, 2026

A Bacterial Oral Feeding Assay with Antibiotic-Treated Mosquitoes

A Bacterial Oral Feeding Assay with Antibiotic-Treated Mosquitoes

Published on: September 12, 2020

Variable microbiomes between mosquito lines are maintained across different environments.

Anastasia Accoti¹, Shannon Quek², Julia Vulcan¹

¹Department of Microbiology and Immunology, University of Texas Medical Branch, Galveston Texas, United States of America.

Plos Neglected Tropical Diseases

|September 25, 2023

Summary

This summary is machine-generated.

Mosquito host genetics shape gut microbiome composition, but environmental factors significantly influence these differences across locations. Host-microbe interactions depend on available environmental bacteria.

More Related Videos

Small-Cage Laboratory Trials of Genetically-Engineered Anopheline Mosquitoes

Small-Cage Laboratory Trials of Genetically-Engineered Anopheline Mosquitoes

Published on: May 1, 2021

Author Spotlight: Optimizing Mosquito Organ Dissection for Studying Symbionts and Vector Microbiomes

Author Spotlight: Optimizing Mosquito Organ Dissection for Studying Symbionts and Vector Microbiomes

Published on: October 4, 2024

Related Experiment Videos

Last Updated: Jul 1, 2026

A Bacterial Oral Feeding Assay with Antibiotic-Treated Mosquitoes

A Bacterial Oral Feeding Assay with Antibiotic-Treated Mosquitoes

Published on: September 12, 2020

Small-Cage Laboratory Trials of Genetically-Engineered Anopheline Mosquitoes

Small-Cage Laboratory Trials of Genetically-Engineered Anopheline Mosquitoes

Published on: May 1, 2021

Author Spotlight: Optimizing Mosquito Organ Dissection for Studying Symbionts and Vector Microbiomes

Author Spotlight: Optimizing Mosquito Organ Dissection for Studying Symbionts and Vector Microbiomes

Published on: October 4, 2024

Area of Science:

Microbiology
Genetics
Ecology

Background:

Mosquito microbiome composition is influenced by host and environment.
The host's role in shaping the mosquito microbiome is not well understood.
Previous studies showed distinct microbiomes in different Aedes aegypti mosquito lines under identical conditions.

Purpose of the Study:

To investigate if Aedes aegypti mosquito lines maintain distinct microbiomes across different environments.
To determine the influence of host genetics versus environment on mosquito microbiome composition.
To assess the conservation of line-specific microbiome properties across varying microbial environments.

Main Methods:

Characterized the microbiome of four Aedes aegypti mosquito lines in two different institutions.
Analyzed alpha diversity, beta diversity, and abundance of specific bacterial taxa.
Compared pairwise differential abundances of taxa between insectaries to assess cross-environment conservation.

Main Results:

Environmental conditions influenced mosquito microbiomes, but distinct line-specific differences persisted within each environment.
Mosquito lines were more similar to other lines from the same insectary than to the same line from a different insectary.
Few differentially abundant taxa were shared across insectaries, indicating limited conservation of line-specific microbiome properties.

Conclusions:

Mosquito host genetics contribute to microbiome differences, but these are heavily modulated by environmental factors and available bacteria.
Host-microbe interactions are context-dependent, varying with the microbial environment.
Line-specific microbiome properties are not consistently conserved across diverse environments.