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Glaucoma is an eye condition characterized by increased intraocular pressure that damages the retina and optic nerve, leading to irreversible blindness if left untreated. The human eye has various components, including the cornea, iris, pupil, lens, and optic nerve. Aqueous humor is secreted by the epithelium of the ciliary body in the posterior chamber and flows through the trabecular meshwork and canal of Schlemm, maintaining normal intraocular pressure. The trabecular meshwork and the canal...
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Related Experiment Video

Updated: Jul 15, 2025

Chronic Intermittent Ethanol Vapor Exposure Paired with Two-Bottle Choice to Model Alcohol Use Disorder
05:12

Chronic Intermittent Ethanol Vapor Exposure Paired with Two-Bottle Choice to Model Alcohol Use Disorder

Published on: June 23, 2023

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Association Between Alcohol Consumption Patterns and Glaucoma in Japan.

Kei Sano1, Ryo Terauchi1, Kota Fukai2

  • 1Department of Ophthalmology, The Jikei University School of Medicine, Tokyo.

Journal of Glaucoma
|September 25, 2023
PubMed
Summary

Alcohol consumption frequency and quantity are linked to a higher prevalence of glaucoma. This association was observed in the Japanese population, particularly among men.

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Area of Science:

  • Ophthalmology
  • Epidemiology
  • Public Health

Background:

  • Glaucoma is a leading cause of irreversible blindness worldwide.
  • Understanding modifiable risk factors for glaucoma is crucial for prevention strategies.
  • Alcohol consumption is a prevalent behavior with potential systemic health effects.

Purpose of the Study:

  • To investigate the association between alcohol consumption patterns and the prevalence of glaucoma.
  • To explore potential gender-specific differences in this association.

Main Methods:

  • A case-control study involving 3207 glaucoma cases and 3207 matched controls from the Japanese population.
  • Data collected included detailed alcohol consumption patterns (frequency, average daily drinks, total lifetime drinks) and confounding factors.
  • Conditional logistic regression models were employed to analyze the odds ratios (ORs) and 95% confidence intervals (CIs).

Main Results:

  • Increased drinking frequency and quantity of alcohol consumption were significantly associated with higher glaucoma prevalence.
  • Specific associations were found for "a few days/week" and "almost every day/week" drinking frequency, "0-2 drinks/day" average consumption, and higher total lifetime drinks.
  • These associations were predominantly observed in men, with no significant links found in women.

Conclusions:

  • Both the frequency and quantity of alcohol intake are associated with an increased risk of glaucoma.
  • The findings highlight significant gender differences in the alcohol-glaucoma relationship, warranting further investigation.
  • Public health recommendations regarding alcohol consumption may need to consider potential ocular health implications.