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Related Concept Videos

Introduction to Hemostasis01:05

Introduction to Hemostasis

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Hemostasis is a complex physiological process that prevents excessive bleeding when a blood vessel is injured. It's crucial for maintaining the integrity of the circulatory system, as it ensures that our blood remains fluid while still within the vascular network and yet clots to prevent blood loss upon vessel injury.
The three phases of hemostasis involve many clotting factors present in plasma and several substances released by platelets and injured tissue cells. It is a fast, localized,...
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Updated: Jul 15, 2025

Microfluidic Flow Chambers Using Reconstituted Blood to Model Hemostasis and Platelet Transfusion In Vitro
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Microfluidic Flow Chambers Using Reconstituted Blood to Model Hemostasis and Platelet Transfusion In Vitro

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Internal Quality Control in Hemostasis Assays.

Christopher Reilly-Stitt1, Ian Jennings1, Steve Kitchen1,2

  • 1UK NEQAS (Blood Coagulation), Sheffield, United Kingdom.

Seminars in Thrombosis and Hemostasis
|September 25, 2023
PubMed
Summary
This summary is machine-generated.

Internal quality control (IQC) is mandatory for hemostasis testing. A survey found all participating UK labs meet IQC standards for their assays.

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Area of Science:

  • Clinical laboratory science
  • Hematology
  • Quality assurance

Background:

  • Internal quality control (IQC) is essential for hemostasis testing accuracy in clinical laboratories.
  • Regulatory standards mandate regular IQC to audit analytical performance of various testing methods.

Purpose of the Study:

  • To review current internal quality control (IQC) practices in hemostasis testing.
  • To assess the benefits, limitations, frequency, materials, and troubleshooting of IQC procedures.

Main Methods:

  • A questionnaire was distributed by the UK National External Quality Assessment Scheme (NEQAS) Blood Coagulation to 1,200 participants.
  • 127 centers provided details on their local IQC testing practices, including frequency, material type, acceptance criteria, and failure protocols.

Main Results:

  • All 127 responding centers confirmed adherence to regular IQC testing standards for their hemostasis assays.
  • The data provided a comprehensive overview of current IQC implementation in UK clinical laboratories.

Conclusions:

  • The study confirms widespread compliance with mandatory IQC requirements in hemostasis testing.
  • The findings provide valuable insights into current IQC practices and adherence to established standards.