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Updated: Jul 15, 2025

Highly Stereoselective Synthesis of 1,6-Ketoesters Mediated by Ionic Liquids: A Three-component Reaction Enabling Rapid Access to a New Class of Low Molecular Weight Gelators

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Published on: November 27, 2015

Glyceryl Diesters.

Preethi S Raj¹, Wilma F Bergfeld², Donald V Belsito²

¹Cosmetic Ingredient Review Senior Scientific Analyst/Writer.

International Journal of Toxicology

|September 26, 2023

Summary

This summary is machine-generated.

The Expert Panel for Cosmetic Ingredient Safety confirmed 17 glyceryl diesters are safe for cosmetic use. This safety assessment considered new studies and updated product usage information.

Keywords:

Cosmetics Glyceryl Diarachidate Glyceryl Dibehenate Glyceryl Dierucate Glyceryl Dihydroxystearate Glyceryl Diisopalmitate Glyceryl Diisostearate Glyceryl Dilaurate Glyceryl Dilinoleate Glyceryl Dioleate Glyceryl Dipalmitate Glyceryl Dipalmitoleate Glyceryl Diricinoleate Glyceryl Distearate Glyceryl Palmitate Lactate Glyceryl Stearate Citrate Glyceryl Stearate Lactate Glyceryl Stearate Succinate Safety

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Published on: November 17, 2011

Area of Science:

Cosmetic Science
Toxicology
Dermatology

Background:

Glyceryl diesters are commonly used in cosmetic formulations.
Previous safety assessments were conducted in 2002.
Updated data on product types and concentrations are crucial for re-evaluation.

Purpose of the Study:

To reassess the safety of 17 glyceryl diesters as cosmetic ingredients.
To incorporate newly available scientific studies into the safety review.
To evaluate current product types and concentrations of use for these ingredients.

Main Methods:

Review of newly available scientific literature post-2002.
Analysis of updated information on cosmetic product types.
Assessment of current usage concentrations for glyceryl diesters.

Main Results:

The Expert Panel reviewed updated safety data.
Consideration of current cosmetic product formulations and ingredient concentrations.
Confirmation of safety based on the reviewed evidence.

Conclusions:

The 17 glyceryl diesters are safe for use in cosmetic products.
Safety is confirmed at the practices of use and concentrations detailed in the report.
The Expert Panel's findings support the continued use of these ingredients.