Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

"Neurotoxic mechanisms of microplastic compounds in Alzheimer's and Parkinson's diseases: A network toxicology and molecular docking study".

Ecotoxicology and environmental safety·2026

Same author

PCK2 as a potential therapeutic target for aggressive MYC-amplified non-WNT/non-SHH medulloblastoma based on tumor continuum.

Acta neuropathologica communications·2026

Same author

Surgical strategy after neoadjuvant immunochemotherapy for central-type NSCLC: restaging-guided versus pre-treatment-guided decision-making.

Translational lung cancer research·2026

Same author

A Nomogram Prediction Model Integrating TEG and Clinical Features for Postoperative Lower Extremity DVT in TF Patients.

Clinical laboratory·2026

Same author

Late-Stage Aryl NCF<sub>3</sub> and SCF<sub>3</sub> Installation Enabled by Coupling Flow-Generated Anions with Aryl Thianthrenium Salts.

Journal of the American Chemical Society·2026

Same author

Phenoxazines with a Phototransferable <i>N</i>-Acetyl Group and Acrylate Linker: Assembly by C-H Activation, Photoconversion to Fluorescent Dyes, Biolabeling, and Super-Resolution Imaging.

Journal of the American Chemical Society·2026

Same journal

Synthetic Porous Carbons for High-Energy, High-Power Supercapacitors.

Chemical reviews·2026

Same journal

Navigating Misfolded Terrain: ER-Associated Degradation of Membrane Proteins.

Chemical reviews·2026

Same journal

Ink Design for Printing Perovskite Solar Cells and Modules.

Chemical reviews·2026

Same journal

Advanced Single-Atom Catalysts for Thermal-Catalytic C1 Chemistry.

Chemical reviews·2026

Same journal

Copper-Dependent Polysaccharide Monooxygenases: Mechanism and Function.

Chemical reviews·2026

Same journal

To Biotic or Abiotic: Biohybrid Systems for Artificial Photosynthesis.

Chemical reviews·2026

See all related articles

Search research articles

Related Experiment Video

Updated: Jul 15, 2025

Tools for Surface Treatment of Silicon Planar Intracortical Microelectrodes

Tools for Surface Treatment of Silicon Planar Intracortical Microelectrodes

Published on: June 8, 2022

Electrochemical Late-Stage Functionalization.

Yulei Wang¹, Suman Dana¹, Hao Long¹

¹Institut für Organische und Biomolekulare Chemie and Wöhler Research Institute for Sustainable Chemistry (WISCh), Georg-August-Universität, Göttingen 37077, Germany.

Chemical Reviews

|September 26, 2023

Summary

This summary is machine-generated.

Late-stage functionalization (LSF) accelerates the creation of new molecules. Electrochemical LSF (eLSF) offers an eco-friendly method for these transformations, gaining significant traction in recent years.

More Related Videos

Bridging the Bio-Electronic Interface with Biofabrication

Bridging the Bio-Electronic Interface with Biofabrication

Published on: June 6, 2012

Electrochemical Preparation of Poly3,4-Ethylenedioxythiophene Layers on Gold Microelectrodes for Uric Acid-Sensing Applications

Electrochemical Preparation of Poly3,4-Ethylenedioxythiophene Layers on Gold Microelectrodes for Uric Acid-Sensing Applications

Published on: July 28, 2021

Related Experiment Videos

Last Updated: Jul 15, 2025

Tools for Surface Treatment of Silicon Planar Intracortical Microelectrodes

Tools for Surface Treatment of Silicon Planar Intracortical Microelectrodes

Published on: June 8, 2022

Bridging the Bio-Electronic Interface with Biofabrication

Bridging the Bio-Electronic Interface with Biofabrication

Published on: June 6, 2012

Electrochemical Preparation of Poly3,4-Ethylenedioxythiophene Layers on Gold Microelectrodes for Uric Acid-Sensing Applications

Electrochemical Preparation of Poly3,4-Ethylenedioxythiophene Layers on Gold Microelectrodes for Uric Acid-Sensing Applications

Published on: July 28, 2021

Area of Science:

Organic Chemistry
Electrochemistry
Medicinal Chemistry

Background:

Late-stage functionalization (LSF) is crucial for developing novel compounds with enhanced properties.
LSF accelerates the discovery of drugs, agrochemicals, and materials.
Electrochemical synthesis offers a sustainable approach to organic transformations.

Purpose of the Study:

To review the recent advancements in electrochemical late-stage functionalization (eLSF).
To summarize the growing momentum and applications of eLSF.
To provide an up-to-date overview of the field until February 2023.

Main Methods:

Literature review of eLSF studies published up to February 2023.
Analysis of key transformations and methodologies in eLSF.
Highlighting the advantages of electrochemical approaches in LSF.

Main Results:

Electrochemical late-stage functionalization (eLSF) has rapidly advanced.
eLSF provides an environmentally friendly alternative for molecular diversification.
The field has seen significant growth and adoption over the past decade.

Conclusions:

eLSF is a powerful and increasingly important strategy in modern organic synthesis.
The methodology enables efficient and sustainable access to complex molecules.
Continued development in eLSF promises further acceleration in chemical innovation.