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Updated: Jul 15, 2025

Three and Four-Dimensional Visualization and Analysis Approaches to Study Vertebrate Axial Elongation and Segmentation
Published on: February 28, 2021
Laying out the mammalian body plan to a T
André Dias1, Alfonso Martinez Arias2
1Systems Bioengineering, MELIS, Universidad Pompeu Fabra, Doctor Aiguader 88, 08003 Barcelona, Spain.
Abstract:
In this issue of Developmental Cell, Schülle et al. address the mechanism that lays down the mammalian body plan and show that the first step in this process is associated with the activity of two T-box transcription factors whose interactions outline territories that will be further elaborated during gastrulation.
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