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Fabrication of deformable patient-specific AAA models by material casting techniques
Maria Nicole Antonuccio1,2,3, Emanuele Gasparotti1, Francesco Bardi1,3,4
1BioCardioLab, Bioengineering Unit - Heart Hospital, Fondazione Toscana "G. Monasterio", Massa, Italy.
Frontiers in Cardiovascular Medicine
|September 27, 2023
Summary
Casting techniques, including lost molds and lost core, successfully created patient-specific abdominal aortic aneurysm (AAA) models. These deformable models are suitable for in-vitro hemodynamic studies and medical imaging applications.
Area of Science:
- Biomedical Engineering
- Medical Imaging
- Fluid Dynamics
Background:
- Abdominal Aortic Aneurysm (AAA) poses life-threatening risks if untreated.
- Patient-specific AAA models are crucial for in-vitro hemodynamic studies, surgical planning, and intervention testing.
- Current additive manufacturing methods struggle to provide the necessary flexibility and transparency for AAA models.
Purpose of the Study:
- To investigate and present casting techniques for fabricating patient-specific, deformable abdominal aortic aneurysm (AAA) models.
- To overcome limitations of direct additive manufacturing for AAA model creation.
- To produce AAA models suitable for advanced in-vitro hemodynamic investigations.
Main Methods:
- Two patient-specific AAA geometries were used to fabricate 3D models via material casting.
- Investigated lost molds and lost core casting approaches for manufacturing deformable AAA models.
- Acquired manufactured models using MRI, CT, ultrasound, and Particle Image Velocimetry (PIV); compared CT data to reference models for accuracy assessment.
Main Results:
- Both lost molds and lost core casting techniques successfully produced deformable AAA models.
- Lost molds casting yielded superior surface finish but was more expensive and time-consuming.
- Lost core casting was more affordable, allowed mold reuse, but resulted in a poorer surface finish.
Conclusions:
- Lost molds and lost core casting are viable methods for creating patient-specific, deformable AAA models.
- These models are suitable for in-vitro hemodynamic investigations, including PIV and medical imaging.
- Casting techniques offer a solution for producing AAA models with desired flexibility and transparency.

