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Updated: Jul 15, 2025

A Gut-on-a-Chip Model to Study the Gut Microbiome-Nervous System Axis
Published on: July 28, 2023
Gastrointestinal microbiome and cholelithiasis: Prospect in the nervous system
Mirella Mancha Chahuara1, Leidhy Dhy Maruja Lopez Tufino1, Carlos Andrés Mugruza-Vassallo2
1Escuela Profesional de Medicina Humana, Universidad Privada San Juan Bautista, Lima Chorrillos 15067, Lima, Peru.
Abstract:
Dan and colleagues recently published research suggesting that the gastrointestinal microbiome (microorganisms and metabolites) in cholelithiasis. They reviewed gallbladder stones, choledocholithiasis, and asymptomatic gallstones. Finally, their discussion was on the gastrointestinal. We focused on complementing the effect of the S1 protein and neuroinflammatory changes caused by severe acute respiratory syndrome coronavirus 2. Our contribution was about to involve the microbiota and the nervous system. They can have similar functions because they have similar pathways and advantages, bearing in mind γ-aminobutyric acid in schizophrenia and serotonin in Parkinson's disease. Therefore in the next few years, more research should be encouraged on the microbiota consequences for development, and mobility.
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