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Updated: Jul 15, 2025

Preparation of Enantiopure Non-Activated Aziridines and Synthesis of Biemamide B, D, and epiallo-Isomuscarine
Published on: June 13, 2022
Application of Metathesis Protocols to the Stereocontrolled Synthesis of some Functionalized β-Amino Esters and
Anas Semghouli1, Melinda Nonn2, Attila M Remete3
1Institute of Organic Chemistry, Stereochemistry Research Group, Research Centre for Natural Sciences, H-, 1117, Budapest, Magyar tudósok krt. 2, Hungary.
Abstract:
In this account our aim was to give an insight into the application of metathesis protocols (ROM, RCM, RCEYM, CM, RRM) for the synthesis of various azaheterocyclic frameworks. Due to the high biological potential and importance in peptide chemistry and drug design of β-amino acids our intention is to give a highlight on the synthetic procedures and transformation of these class of compounds with the above-mentioned metathesis strategies with emphasis on selectivity, stereocontrol, substrate-directing effect or functional group tolerance.
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