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Updated: Jul 15, 2025

Imaging Features of Systemic Sclerosis-Associated Interstitial Lung Disease
Published on: June 16, 2020
[Interstitial pneumonia and venlafaxine use].
Antidepressants, like venlafaxine, can rarely cause interstitial pneumonia. Psychiatrists should be aware of this potential side effect, even though it is uncommon.
Area of Science:
- Pharmacology
- Pulmonology
- Psychiatry
Background:
- Interstitial pneumonia is a serious lung condition.
- Antidepressants are widely prescribed medications.
- Rare adverse drug reactions can occur with any medication.
Purpose of the Study:
- To report a case of venlafaxine-induced interstitial pneumonia.
- To review existing literature on antidepressant-induced interstitial pneumonia.
- To raise awareness among psychiatrists about this potential side effect.
Main Methods:
- Case report of a 71-year-old woman.
- Literature review of venlafaxine-induced interstitial pneumonia.
- Review of case reports for other antidepressant-induced lung conditions.
Main Results:
- A case of interstitial pneumonia was diagnosed and attributed to venlafaxine.
- Thirteen previous cases of venlafaxine-induced interstitial pneumonia were identified in the literature.
- Other antidepressants have also been associated with interstitial pneumonia.
Conclusions:
- Antidepressants are a potential cause of interstitial pneumonia, although rare.
- Psychiatrists should consider drug-induced lung disease in patients on antidepressants with respiratory symptoms.
- Awareness of this rare adverse effect is crucial for clinical practice.
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