Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Development of synthetic bacteriophages with extended host range to overcome resistant Klebsiella pneumoniae.

Scientific reports·2026
Same author

Optimization of the Quantum-Si Platinum Single-Molecule Protein Sequencing Platform Toward Improved Complex-Matrix Protein Identification.

ACS omega·2026
Same author

Catalytic Efficiency for the Chemoenzymatic Synthesis of Core Human Milk Oligosaccharides and Analogs via Sugar Oxazolines.

Journal of agricultural and food chemistry·2026
Same author

Artificial intelligence aided design of peptides with custom secondary structure motifs and reduced amino acid alphabets.

bioRxiv : the preprint server for biology·2026
Same author

Quantum Dot and Nucleic Acid Optical Readout for Cell-Free Biosensing.

ACS nanoscience Au·2026
Same author

Engineered phages for selective adsorption of rare earth elements.

Scientific reports·2025

Related Experiment Video

Updated: Jul 15, 2025

Bacterial Cell Culture at the Single-cell Level Inside Giant Vesicles
07:33

Bacterial Cell Culture at the Single-cell Level Inside Giant Vesicles

Published on: April 30, 2019

7.0K

Bacterial Membrane Vesicles for In Vitro Catalysis.

Meghna Thakur1,2, Scott N Dean2, Julie C Caruana3

  • 1College of Science, George Mason University, Fairfax, VA 22030, USA.

Bioengineering (Basel, Switzerland)
|September 28, 2023
PubMed
Summary

Bacterial membrane vesicles offer a promising platform for biocatalysis, enhancing enzyme stability and efficiency in biomanufacturing. This review explores their natural roles and engineered applications for industrial biotechnology.

Keywords:
biocatalysisbiomanufacturingouter membrane vesicles (OMVs)

More Related Videos

Mycobacterium tuberculosis Extracellular Vesicle Enrichment through Size Exclusion Chromatography
09:29

Mycobacterium tuberculosis Extracellular Vesicle Enrichment through Size Exclusion Chromatography

Published on: May 19, 2022

2.4K
The Encapsulation of Cell-free Transcription and Translation Machinery in Vesicles for the Construction of Cellular Mimics
10:28

The Encapsulation of Cell-free Transcription and Translation Machinery in Vesicles for the Construction of Cellular Mimics

Published on: October 21, 2013

15.2K

Related Experiment Videos

Last Updated: Jul 15, 2025

Bacterial Cell Culture at the Single-cell Level Inside Giant Vesicles
07:33

Bacterial Cell Culture at the Single-cell Level Inside Giant Vesicles

Published on: April 30, 2019

7.0K
Mycobacterium tuberculosis Extracellular Vesicle Enrichment through Size Exclusion Chromatography
09:29

Mycobacterium tuberculosis Extracellular Vesicle Enrichment through Size Exclusion Chromatography

Published on: May 19, 2022

2.4K
The Encapsulation of Cell-free Transcription and Translation Machinery in Vesicles for the Construction of Cellular Mimics
10:28

The Encapsulation of Cell-free Transcription and Translation Machinery in Vesicles for the Construction of Cellular Mimics

Published on: October 21, 2013

15.2K

Area of Science:

  • Biotechnology
  • Biomanufacturing
  • Enzyme Engineering

Background:

  • Biological systems are increasingly utilized in manufacturing and medicine due to a deeper understanding of their capabilities and constraints.
  • Biomanufacturing leverages biological systems for producing biomolecules and chemical precursors, offering advantages over harsh chemical processes.
  • Challenges in biological production include product toxicity and reduced efficiency from competing metabolic pathways.

Purpose of the Study:

  • To introduce biocatalysis and bacterial membrane vesicles.
  • To highlight the natural catalytic roles of bacterial membrane vesicles.
  • To review engineered vesicle-enzyme systems for biocatalysis and discuss future directions in biotechnology and biomanufacturing.

Main Methods:

  • Review of existing literature on biocatalysis and bacterial membrane vesicles.
  • Analysis of natural microbial strategies for enzyme secretion and encapsulation.
  • Examination of engineered vesicle-enzyme systems for enhanced catalytic performance.

Main Results:

  • Microbes naturally use membrane vesicles to encapsulate enzymes for environmental conditioning and nutrient acquisition.
  • Vesicle encapsulation enhances enzyme stability, solvent tolerance, and overall catalytic efficiency.
  • Engineered bacterial membrane vesicles show significant potential for industrial biocatalysis.

Conclusions:

  • Bacterial membrane vesicles represent a powerful and versatile tool for advancing biotechnology and biomanufacturing.
  • Further research and engineering of these systems can overcome current limitations in biological production.
  • Vesicle-based biocatalysis offers a sustainable and efficient alternative to traditional chemical manufacturing.