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Calcium, Phosphorus and Magnesium Abnormalities Associated with COVID-19 Infection, and Beyond
Lucreția Anghel1,2, Corina Manole1,2, Aurel Nechita1,3
1Clinical Medical Department, Faculty of Medicine and Pharmacy, 'Dunarea de Jos' University, 800008 Galati, Romania.
Abstract:
The coronavirus disease (COVID-19) pandemic caused by the novel coronavirus SARS-CoV-2 has had a profound impact on global health, leading to a surge in research to better understand the pathophysiology of the disease. Among the various aspects under investigation, disruptions in mineral homeostasis have emerged as a critical area of interest. This review aims to provide an overview of the current evidence linking calcium, phosphorus and magnesium abnormalities with COVID-19 infection and explores the potential implications beyond the acute phase of the disease. Beyond the acute phase of COVID-19, evidence suggests a potential impact of these mineral abnormalities on long-term health outcomes. Persistent alterations in calcium, phosphorus and magnesium levels have been linked to increased cardiovascular risk, skeletal complications and metabolic disorders, warranting continuous monitoring and management in post-COVID-19 patients.
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