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Updated: Jul 15, 2025
05:51
Measuring the Carotid to Femoral Pulse Wave Velocity Cf-PWV to Evaluate Arterial Stiffness
Published on: May 3, 2018
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One Step Back from Bedside to the Bench-How Do Different Arterial Stiffness Parameters Behave in Relation to
Nóra Obajed Al-Ali1, Sára Rebeka Tóth2, László Váróczy1
1Division of Hematology, Department of Internal Medicine, Faculty of Medicine, University of Debrecen, 4032 Debrecen, Hungary.
Diagnostics (Basel, Switzerland)
|September 28, 2023
Summary
Directly measured arterial stiffness parameters like distensibility coefficient (DC) and pulse wave velocity (PWV) are stable. However, oscillometric PWV can be affected by interventions due to wave reflection changes.
Area of Science:
- Cardiovascular Physiology
- Vascular Mechanics
- Biomedical Engineering
Background:
- Arterial stiffening is a key indicator of cardiovascular risk.
- The dynamic stability of arterial stiffness parameters under varying physiological conditions is not well understood.
- Commonly used ultrasound-based and oscillometric methods assess arterial elasticity.
Purpose of the Study:
- To evaluate the stability of large artery elasticity parameters using ultrasound and oscillometric methods.
- To investigate the influence of peripheral resistance modulation (via heating and compression) on these parameters.
- To assess the reliability of these measurements in dynamic physiological states.
Main Methods:
- Fifteen young males were studied under resting, extremity heating, and external compression conditions.
- Ultrasound-based and oscillometric techniques were used to measure arterial stiffness parameters.
- Distensibility coefficient (DC), carotid-femoral pulse wave velocity (PWV), and oscillometric PWV (oPWV) were analyzed.
Main Results:
- Distensibility coefficient (DC) showed acceptable stability across conditions.
- Ultrasound-measured PWV demonstrated excellent intersession stability.
- Oscillometric PWV (oPWV) exhibited significant changes related to wave reflection, influenced by physical interventions.
Conclusions:
- Directly measured elastic parameters (DC, ultrasound PWV) are stable despite peripheral resistance modulation.
- Indirectly measured oPWV is sensitive to physical interventions, highlighting the impact of wave reflection.
- Rigorous standardization of the measurement environment is crucial for oscillometric assessments; the reflection point is dynamic.
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