Estimating the Risk of Attention Deficit Hyperactivity Disorder (ADHD) in Parents of Children with ADHD and the Association with Their Children's Disease Severity and Adherence to Medication
Jananheendaran Ragadran1, Norazlin Kamal Nor1, Juriza Ismail1
1Department of Paediatrics, Universiti Kebangsaan Malaysia Medical Faculty, Kuala Lumpur 56000, Malaysia.
Insights
A third of children with Attention Deficit Hyperactivity Disorder (ADHD) have parents with ADHD. Parental ADHD is linked to increased child ADHD severity and behavioral issues, but not medication adherence.
Area of Science:
- Neurodevelopmental Disorders
- Child and Adolescent Psychiatry
- Genetics and Heritability
Background:
- Attention Deficit Hyperactivity Disorder (ADHD) is a neurodevelopmental disorder affecting attention, hyperactivity, and impulsivity.
- Familial aggregation of ADHD is significant, with up to 50% of affected children having a parent with ADHD.
- Understanding the genetic and environmental factors contributing to ADHD heritability is crucial for effective intervention.
Purpose of the Study:
- To estimate the prevalence of ADHD among parents of children diagnosed with ADHD.
- To investigate the association between parental ADHD and the severity of ADHD in children.
- To determine the correlation between parental ADHD and children's medication adherence.
Main Methods:
- A cross-sectional study involving parents of children and adolescents diagnosed with ADHD at University Kebangsaan Malaysia Medical Centre.
- Participants completed the Conners' Adult ADHD Rating Scale (CAARS), Vanderbilt ADHD Parent Rating Scale, and Medication Adherence Report Scale (MARS).
- Data were collected between June and August 2022.
Main Results:
- Out of 45 children with ADHD, 15 parents (33%) were identified as having ADHD.
- Children with ADHD parents exhibited significantly higher total ADHD severity (p=0.047) and more difficult home behaviors (p=0.036).
- Parental ADHD scores for inattention and self-care problems correlated positively with children's academic performance and behavioral challenges.
Conclusions:
- Approximately one-third of children with ADHD have parents who also have the disorder.
- Parental ADHD is associated with increased ADHD symptom severity and behavioral problems in children.
- No statistically significant association was found between parental ADHD and children's medication adherence.
Background:
Attention deficit hyperactivity disorder (ADHD) is characterised by inattentiveness, hyperactivity, and impulsivity. Up to half of the affected children have a parent with ADHD. In this study, the risk of ADHD among parents of ADHD children was estimated. The associations between parental ADHD and child ADHD severity and medication adherence were determined.
Methodology:
Parents of children and adolescents diagnosed with ADHD attending the University Kebangsaan Malaysia Medical Centre (UKMMC) were recruited between June to August 2022 and the administered Conners' Adult ADHD Rating Scale (CAARS) self-report short form, Vanderbilt ADHD Parent Rating Scale (performance section), and Medication Adherence Report Scale (MARS).
Results:
Forty-five children with ADHD were recruited and 15 out of 45 (33%) parents were detected to have ADHD. ADHD severity was worse in children with ADHD parents for total severity (mean of 34.67 vs. 29.13, p = 0.047) and difficult behaviours at home (mean of 7.87 vs. 6.27, p = 0.036). The children's academic performance and behavioural challenges at home and school were positively correlated with the parental ADHD scores for 'inattention' and 'problems with self-care' subscales.
Conclusions:
A total of 33% of ADHD children had parents with ADHD. ADHD children with ADHD parents were more likely to have behavioural problems at home and more severe ADHD. However, no statistical significance was noted with medication adherence.
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