Cystitis and Utipro® Plus: Real-World Evidence
Karel Kostev1,2, Tommaso Cai3,4
1Epidemiology, IQVIA S.L., 60549 Frankfurt am Main, Germany.
Healthcare (Basel, Switzerland)
|September 28, 2023
Summary
This study shows that Utipro® Plus, a medical device, can reduce urinary tract infection (UTI) episodes and antibiotic use. It also decreases sick leave days for individuals with uncomplicated cystitis.
Area of Science:
- Urology
- Infectious Diseases
- Pharmacology
Background:
- Rising antibiotic resistance in urinary tract infection (UTI) pathogens necessitates alternative treatments.
- Uncomplicated cystitis management requires novel strategies beyond antibiotics.
Purpose of the Study:
- To assess the efficacy of Utipro® Plus, a medical device containing xyloglucan, hibiscus, and propolis.
- To evaluate its impact on reducing symptomatic urinary tract infection (UTI) episodes.
- To determine its effect on antibiotic prescriptions and sick leave duration.
Main Methods:
- Retrospective, cross-sectional study utilizing German office-based physician data (IQVIA Disease Analyzer).
- Analysis of 3586 patients diagnosed with UTI and treated with Utipro® Plus between January 2015 and December 2020.
- Comparison of UTI incidence, antibiotic prescriptions, and sick leave days in the 12 months before and after treatment initiation.
Main Results:
- Significant reduction in UTI diagnosis proportion from 79.4% to 36.4% (p < 0.001) within 12 months post-treatment.
- Marked decrease in antibiotic prescriptions from 33.5% to 22.1% (p < 0.001).
- Reduction in the proportion of patients with sick leave days from 4.1% to 2.7%.
Conclusions:
- Utipro® Plus demonstrates effectiveness in decreasing urinary tract infection (UTI) recurrence.
- The medical device contributes to reducing antibiotic prescriptions.
- It alleviates the disease burden associated with uncomplicated cystitis.
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