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Updated: Jul 15, 2025
The Intra-Aortic Balloon Pump
Published on: February 5, 2021
Intra-Aortic Balloon Pump among Shockable Out-of-Hospital Cardiac Arrest Patients: A Propensity-Weighted Analysis in
Satoshi Yoshimura1, Takeyuki Kiguchi2, Taro Irisawa3
1Department of Preventive Services, Kyoto University School of Public Health, Kyoto 606-8317, Japan.
Insights
Intra-aortic balloon pump (IABP) use in non-traumatic shockable out-of-hospital cardiac arrest (OHCA) patients did not improve 1-month survival with favorable neurological outcomes. This study found no significant association after statistical adjustment.
Area of Science:
- Cardiology
- Emergency Medicine
- Critical Care Medicine
Background:
- The effectiveness of intra-aortic balloon pump (IABP) in shockable out-of-hospital cardiac arrest (OHCA) remains under-investigated.
- Limited data exists on IABP's impact on neurological outcomes in non-traumatic OHCA patients.
Purpose of the Study:
- To investigate the association between IABP use and favorable neurological outcomes in adult patients with non-traumatic, shockable OHCA.
- To determine if IABP improves 1-month survival with good neurological function post-cardiac arrest.
Main Methods:
- Utilized data from the Japanese Association for Acute Medicine Out-of-Hospital Cardiac Arrest registry (2014-2019).
- Included adult patients with non-traumatic, shockable OHCA who received resuscitation.
- Employed propensity score inverse probability of weighting (IPW) to analyze the association between IABP and the primary outcome.
Main Results:
- A total of 2738 adult patients with non-traumatic shockable OHCA were analyzed.
- In the original cohort, IABP use was associated with lower survival (OR 0.57).
- After propensity score weighting, IABP use showed no significant difference in favorable neurological outcomes (OR 1.18).
Conclusions:
- Intra-aortic balloon pump (IABP) use was not associated with improved 1-month survival with favorable neurological outcomes in adult non-traumatic shockable OHCA patients.
- The findings suggest IABP may not be beneficial for this specific patient population.
Background:
The effectiveness of IABP for shockable out-of-hospital cardiac arrest (OHCA) has not been extensively investigated. This study aimed to investigate whether the use of an intra-aortic balloon pump (IABP) for non-traumatic shockable OHCA patients was associated with favorable neurological outcomes.
Methods:
From the Japanese Association for Acute Medicine Out-of-Hospital Cardiac Arrest registry, a nationwide multicenter prospective registry, we enrolled adult patients with non-traumatic and shockable OHCA for whom resuscitation was attempted, and who were transported to participating hospitals between 2014 and 2019. The primary outcome was 1-month survival with favorable neurological outcomes after OHCA. After adopting the propensity score (PS) inverse probability of weighting (IPW), we evaluated the association between IABP and favorable neurological outcomes.
Results:
Of 57,754 patients in the database, we included a total of 2738 adult non-traumatic shockable patients. In the original cohort, the primary outcome was lower in the IABP group (OR with 95% confidence intervals (CIs)), 0.57 (0.48-0.68), whereas, in the IPW cohort, it was not different between patients with and without IABP (OR, 1.18; 95% CI, 0.91-1.53).
Conclusion:
In adult patients with non-traumatic shockable OHCA, IABP use was not associated with 1-month survival with favorable neurological outcomes.
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