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Pedunculated Focal Nodular Hyperplasia: When in Doubt, Should We Cut It Out?
Christos Tsalikidis1, Athanasia Mitsala1, George Pappas-Gogos1
1Second Department of Surgery, University General Hospital of Alexandroupolis, Democritus University of Thrace Medical School, 68100 Alexandroupolis, Greece.
Journal of Clinical Medicine
|September 28, 2023
Summary
Pedunculated focal nodular hyperplasia (FNH) is a rare liver tumor variant. This study summarizes adult and pediatric cases, highlighting diagnostic imaging and surgical indications for better clinical outcomes.
Area of Science:
- Hepatology
- Surgical Oncology
- Diagnostic Imaging
Background:
- Focal nodular hyperplasia (FNH) is the second most common benign liver tumor, typically found incidentally.
- Pedunculated FNH, a rare variant, presents diagnostic challenges and potential complications.
- FNH exhibits a high female predominance.
Purpose of the Study:
- To comprehensively summarize data on pedunculated FNH in adults and children.
- To review therapeutic options for pedunculated FNH.
- To propose a management algorithm for suspected FNH.
Main Methods:
- Literature review of pedunculated FNH cases.
- Analysis of diagnostic imaging modalities.
- Evaluation of surgical indications and outcomes.
Main Results:
- Pedunculated FNH is rare, associated with complications, and poses diagnostic difficulties.
- Imaging techniques are crucial for diagnosis.
- Surgery is indicated for symptomatic cases, diagnostic uncertainty, or high complication risk.
Conclusions:
- Awareness of pedunculated FNH is vital for timely diagnosis and management.
- A high index of suspicion is necessary for this uncommon cause of acute abdomen.
- The proposed algorithm aids in managing suspected FNH lesions.

