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Electrospun PVA Fibers for Drug Delivery: A Review
Fatima T Zahra1, Quincy Quick2, Richard Mu1
1TIGER Institute, Tennessee State University, Nashville, TN 37209, USA.
Polymers
|September 28, 2023
Summary
Electrospun Polyvinyl Alcohol (PVA) shows great promise for advanced drug delivery systems due to its favorable properties. This review highlights PVA
Area of Science:
- Biomedical Science
- Materials Science
- Nanotechnology
Background:
- Drug delivery systems (DDSs) are crucial in biomedical science.
- Electrospinning is a key technique for developing advanced DDSs.
- Various polymers like PEG, PLGA, PLA, and PCA have been used in electrospun DDSs.
Purpose of the Study:
- To review recent advances in electrospun drug delivery systems.
- To highlight the potential of Polyvinyl Alcohol (PVA) in DDSs.
- To summarize the properties and applications of PVA-based DDSs.
Main Methods:
- Review of existing literature on electrospun drug delivery systems.
- Focus on Polyvinyl Alcohol (PVA) and its composites.
- Analysis of PVA's properties relevant to drug delivery.
Main Results:
- Polyvinyl Alcohol (PVA) exhibits excellent biocompatibility, biodegradability, and mechanical properties for DDSs.
- PVA shows promise both as a standalone material and when combined with other polymers like chitosan and PCL.
- Electrospun PVA facilitates effective drug encapsulation and release.
Conclusions:
- Electrospun PVA is a highly promising material for next-generation drug delivery systems.
- The unique properties of PVA make it suitable for various therapeutic applications.
- Further research into PVA-based DDSs is warranted to optimize their clinical potential.
