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Updated: Jul 15, 2025

Author Spotlight: Investigating Fungal Pathogenicity Mechanisms in Maize
Published on: September 15, 2023
Distinct dynamics of the nucleolus in response to nutrient availability and during development in the rice blast
Eunbyeol Cho1, Song Hee Lee1,2, Ralph A Dean3
1Department of Biotechnology, College of Life and Applied Sciences, Yeungnam University , Gyeongsan, Gyeongbuk, South Korea.
Importance:
The nucleolus is a dynamic subnuclear structure that is involved in many fundamental processes of the nucleus. In higher eukaryotic cells, the size and shape of nucleoli correlate with nucleolar activities. For fungi, knowledge of the nucleolus and its functions is primarily gleaned from budding yeast. Whether such correlation is conserved and how nucleolar functions are regulated in filamentous fungi including important human and crop pathogens are largely unknown. Our observations reveal that the dynamics of nucleolus in a model plant pathogenic fungus, Magnaporthe oryzae, is distinct from those of animal and yeast nucleoli under low nutrient availability and during pathogenic development. Our data not only provide new insight into the nucleoli in filamentous fungi but also highlight the need for investigating how nucleolar dynamics is regulated in comparison to other eukaryotes.
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