Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Factors Affecting the Risk of Infection01:26

Factors Affecting the Risk of Infection

11.9K
The hosts' susceptibility to infection depends on several factors. The integrity of the skin and mucous membranes helps protect the body against microbial attacks. When the skin is altered, the chance of infection, limb loss, and even death increases.
The integrity and count of the white blood cells help the body resist pathogens and fight infection. When impaired, it reduces the body's resistance to pathogens. The acidic pH levels of the gastrointestinal, genitourinary tracts, and skin...
11.9K
Healthcare Associated Infections I: Iatrogenic, Exogenic and Endogenic01:26

Healthcare Associated Infections I: Iatrogenic, Exogenic and Endogenic

4.2K
Healthcare-associated infections (HAIs) occur in a healthcare facility while a person receives care for another ailment. This category also includes work-related infections among healthcare staff.
HAIs significantly increase the cost of health care. Extended stays in healthcare institutions, increased disability, increased costs of medications, including specialized antibiotics, and prolonged recovery times add to the patient's expenses and the healthcare institution and funding bodies.
4.2K
Healthcare Associated Infections II: Preventive Measures01:22

Healthcare Associated Infections II: Preventive Measures

2.7K
Essential infection prevention measures are based on the knowledge of the infection chain, the modes of transmission in healthcare settings, and the use of the best practices in all healthcare settings. Compulsory public reporting of healthcare-associated infection rates is needed to allow individuals and the community to make informed choices regarding selecting a healthcare facility.
The best practices for preventing healthcare-associated infections include hand hygiene, patient risk...
2.7K
Bacterial Flora of the Large Intestine01:29

Bacterial Flora of the Large Intestine

500
The gut microbiome is formed by a vast and diverse community of bacteria that colonizes our large intestine. These bacteria start residing in the gut from birth and continue diversifying throughout life, influenced by factors such as diet, lifestyle, and stress. The gut bacterial community also includes bacteria from food and those that enter the colon through the anus.
The normal gut flora of the colon plays a critical role in generating essential vitamins such as vitamins K, B5, and B7.
500
Prevalence and Incidence01:08

Prevalence and Incidence

619
In statistical epidemiology and health sciences, two essential metrics—prevalence and incidence—are fundamental for understanding disease dynamics within a population. These measures enable public health officials, epidemiologists, and researchers to assess the burden of diseases, allocate resources effectively, and design impactful public health policies and interventions.
Prevalence indicates the proportion of individuals in a population who have a specific disease or health...
619
Development of Antibiotic Resistance01:30

Development of Antibiotic Resistance

33
Antibiotic resistance is a major public health concern that arises when bacteria evolve mechanisms to withstand the effects of antibiotic treatments. This resistance can be intrinsic, acquired through genetic mutations, or transferred between bacteria via horizontal gene transfer. The development of antibiotic resistance poses significant challenges in treating bacterial infections and necessitates ongoing research to develop new therapeutic strategies.Intrinsic resistance occurs when bacterial...
33

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Effectiveness and treatment patterns of isavuconazole in real-world use in Mexico: A retrospective study of 25 patients.

Revista iberoamericana de micologia·2026
Same author

Determination of copy number variations and affected gene networks in breast cancer.

Biomedical reports·2026
Same author

Prevalence and Association of Liver Steatosis and Non-Alcoholic Pancreatic Steatosis in Very High Cardiovascular Risk.

Diseases (Basel, Switzerland)·2026
Same author

Managing Breakthrough Fungal Infections in Hematologic Patients: Determinants and Practical Management from a Latin American Perspective on Behalf of INFOCUS LATAM-ISHAM Working Group.

Microorganisms·2026
Same author

Surveillance of carbapenem-resistant Pseudomonas aeruginosa isolates obtained from patients treated in a paediatric hospital in Mexico.

Scientific reports·2026
Same author

Current management of MASLD in type 2 diabetes.

Hormones (Athens, Greece)·2026

Related Experiment Video

Updated: Jul 15, 2025

Cefoperazone-treated Mouse Model of Clinically-relevant Clostridium difficile Strain R20291
06:51

Cefoperazone-treated Mouse Model of Clinically-relevant Clostridium difficile Strain R20291

Published on: December 10, 2016

12.6K

Clostridioides Difficile in Latin America: An Epidemiological Overview.

Claudia G Morales-Olvera1,2, Lorena Lanz-Zubiría3, Emmanuel Aguilar-Zamora4,5

  • 1Translational Research Unit. Medica Sur Clinic & Foundation, Mexico City, Mexico.

Current Microbiology
|September 28, 2023
PubMed
Summary

Clostridioides difficile infection, a major cause of hospital-associated diarrhea, is rising in Latin America due to new strains and inconsistent antibiotic guidelines. Enhanced epidemiological surveillance is crucial for control.

More Related Videos

A Protocol to Characterize the Morphological Changes of Clostridium difficile in Response to Antibiotic Treatment
12:58

A Protocol to Characterize the Morphological Changes of Clostridium difficile in Response to Antibiotic Treatment

Published on: May 25, 2017

9.0K
A Protein Microarray Assay for Serological Determination of Antigen-specific Antibody Responses Following Clostridium difficile Infection
09:12

A Protein Microarray Assay for Serological Determination of Antigen-specific Antibody Responses Following Clostridium difficile Infection

Published on: June 15, 2018

10.2K

Related Experiment Videos

Last Updated: Jul 15, 2025

Cefoperazone-treated Mouse Model of Clinically-relevant Clostridium difficile Strain R20291
06:51

Cefoperazone-treated Mouse Model of Clinically-relevant Clostridium difficile Strain R20291

Published on: December 10, 2016

12.6K
A Protocol to Characterize the Morphological Changes of Clostridium difficile in Response to Antibiotic Treatment
12:58

A Protocol to Characterize the Morphological Changes of Clostridium difficile in Response to Antibiotic Treatment

Published on: May 25, 2017

9.0K
A Protein Microarray Assay for Serological Determination of Antigen-specific Antibody Responses Following Clostridium difficile Infection
09:12

A Protein Microarray Assay for Serological Determination of Antigen-specific Antibody Responses Following Clostridium difficile Infection

Published on: June 15, 2018

10.2K

Area of Science:

  • Infectious Diseases
  • Microbiology
  • Public Health

Background:

  • Clostridioides difficile infection (CDI) is a leading cause of nosocomial diarrhea globally.
  • Antibiotic use is a primary risk factor for CDI.
  • Rising incidence of CDI in Latin America is a growing concern.

Purpose of the Study:

  • To review current information on Clostridioides difficile.
  • To highlight the increasing prevalence of epidemic strains (e.g., RT027/NAP1/ST1) in Latin America.
  • To emphasize the need for robust epidemiological surveillance of CDI in the region.

Main Methods:

  • Literature review of recent studies on Clostridioides difficile.
  • Analysis of epidemiological trends in Latin American countries.
  • Examination of factors contributing to CDI spread, including antibiotic use and diagnostic challenges.

Main Results:

  • Emergence and spread of specific epidemic Clostridioides difficile strains in Latin America.
  • Appearance of endemic multi-drug-resistant strains.
  • Inconsistent diagnostic algorithms and antibiotic guidelines contribute to the problem.

Conclusions:

  • Clostridioides difficile infection poses a significant and increasing threat in Latin America.
  • Effective control requires addressing strain emergence, antibiotic stewardship, and diagnostic practices.
  • Strengthening epidemiological surveillance is essential for managing CDI in this region.