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Atypical diffuse large B-cell lymphoma, primary splenic lymphoma variant; a case report
Muzi Meng1, Cesar A Riera2, Jorge Mosquera2
1General Surgery, BronxCare Health System, Bronx, NY, USA; School of Medicine, American University of the Caribbean, Cupecoy, St. Maarten, the Netherlands.
International Journal of Surgery Case Reports
|September 28, 2023
Summary
Primary splenic diffuse large B-cell lymphoma (DLBCL) is a rare cancer. Diagnosis requires excluding other sites, and treatment involves splenectomy and adjuvant therapy for optimal outcomes.
Area of Science:
- Hematology
- Oncology
- Pathology
Background:
- Primary splenic lymphoma (PSL) is rare, comprising ~1% of non-Hodgkin lymphomas (NHLs).
- Diffuse large B-cell lymphoma (DLBCL) is the most common histological subtype of PSL and NHLs.
- DLBCL is an aggressive, heterogeneous entity with diverse morphological variants.
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