Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Role of Skin in Vitamin D Synthesis01:23

Role of Skin in Vitamin D Synthesis

5.3K
The skin plays a crucial role in the synthesis of vitamin D, a vital nutrient for various physiological processes in the body. Vitamin D is unique because it can be synthesized in the skin through a series of chemical reactions triggered by exposure to ultraviolet B (UVB) radiation from sunlight.
The solar UV B rays (290-315 nm) are absorbed by the skin, and 7-dehydrocholesterol (provitamin D3) photolyzes it to previtamin D3, which undergoes a rapid transformation to vitamin...
5.3K
Role of Vitamins in Maintaining Bone Health01:25

Role of Vitamins in Maintaining Bone Health

3.4K
The growth and maintenance of bone are regulated by a combination of nutritional factors, including vitamins, such as vitamin A, B12, C, D, and K.
Vitamin A
Vitamin A is involved in the process of bone remodeling. Retinoic acid, the active metabolite of Vitamin A, has nuclear receptors in osteoblasts and osteoclasts, which are involved in bone remodeling.
Vitamin B12
Vitamin B12 acts as a cofactor during the formation of osteoblast-related proteins, such as osteocalcin. Vitamin B12 plays a role...
3.4K
Skeleton and Calcium Homeostasis01:21

Skeleton and Calcium Homeostasis

4.6K
Calcium is not only the most abundant mineral in bone but also the most abundant mineral in the human body. Calcium ions are needed for bone mineralization, tooth health, heart rate regulation and strength of contraction, blood coagulation, the contraction of smooth and skeletal muscle cells, and the regulation of nerve impulse conduction. The average calcium level in the blood is about 10 mg/dL. When the body cannot maintain this level, a person will experience hypo or hypercalcemia.
4.6K
Connective Tissue Cell Types01:22

Connective Tissue Cell Types

3.3K
Connective tissue develops from the mesoderm of a developing embryo and consists of cells, fibers, and ground substance: a gel-like material containing large complexes of carbohydrates and proteins. Connective tissue was first identified as a separate tissue family in the 18th century, and Johannes Peter Muller coined the term connective tissue.
Fat cells (adipocytes), smooth muscle cells (myoblasts), and bone cells (osteoblasts) are some connective tissue cell types. Some immune system cells...
3.3K
Insulin: Dosing Regimen and Adverse Effects01:16

Insulin: Dosing Regimen and Adverse Effects

198
Insulin-replacement therapy usually includes both long-acting insulin (basal) and short-acting insulin (to cater to postprandial needs). In a diverse group of type 1 diabetes patients, the average daily insulin dose is typically 0.5-0.7 units/kg body weight. However, obese patients and pubertal adolescents may need more due to insulin resistance.
The basal dose constitutes about 40%-50% of the total daily dose, with the rest as premeal insulin. The mealtime insulin dose should mirror...
198
Hormones and Bone Tissue01:17

Hormones and Bone Tissue

2.7K
The endocrine system produces and secretes hormones, which interact with the skeletal system. These hormones control bone growth, maintain bone once it is formed, and remodel it.
Hormones That Influence Osteoblasts and/or Maintain the Matrix
Several hormones are necessary for controlling bone growth and maintaining the bone matrix. The pituitary gland secretes growth hormone (GH), which, as its name implies, controls bone growth. This happens in several ways: first, it triggers chondrocyte...
2.7K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Gender-Attributed Persona Prompts and the Diagnostic Accuracy of Proprietary and Open-Weight Large Language Models in Chagas Disease and Visceral Leishmaniasis: A Paired Experimental Study.

Healthcare (Basel, Switzerland)·2026
Same author

A Series of Severe and Critical COVID-19 Cases in Hospitalized, Unvaccinated Children: Clinical Findings and Hospital Care.

Epidemiologia (Basel, Switzerland)·2025
Same author

Sarcopenic obesity and physical function in acromegaly: impact of disease control and evaluation using dual X-ray absorptiometry and multifrequency bioelectrical impedance analysis.

Journal of endocrinological investigation·2025
Same author

Nutrition risk stratification and metabolic disorders in patients on parenteral nutrition.

Revista da Escola de Enfermagem da U S P·2025
Same author

Severity Profile of COVID-19 in Hospitalized Pediatric Patients.

Children (Basel, Switzerland)·2024
Same author

Association between malnutrition-inflammation score (MIS) and quality of life in elderly hemodyalisis patients.

Jornal brasileiro de nefrologia·2024

Related Experiment Video

Updated: Jul 15, 2025

Isolation of Mesenchymal Stem Cells from Human Alveolar Periosteum and Effects of Vitamin D on Osteogenic Activity of Periosteum-derived Cells
06:47

Isolation of Mesenchymal Stem Cells from Human Alveolar Periosteum and Effects of Vitamin D on Osteogenic Activity of Periosteum-derived Cells

Published on: May 4, 2018

9.4K

Vitamin D Concentration Changes after Bariatric Surgery.

Vanessa Mayana Alves Baad1, Narriane Chaves Pereira de Holanda1,2, Juliana Fonseca Nogueira Alves3

  • 1Faculty of Medical Sciences, University of Pernambuco, Recife, Pernambuco, Brazil.

Journal of Obesity
|September 29, 2023
PubMed
Summary

Bariatric surgery impacts vitamin D levels and body composition. Both Roux-en-Y gastric bypass and vertical sleeve gastrectomy effectively reduce fat mass, with similar post-surgical vitamin D outcomes.

More Related Videos

Roux-en-Y Gastric Bypass Operation in Rats
07:37

Roux-en-Y Gastric Bypass Operation in Rats

Published on: June 11, 2012

23.6K
Sleeve Gastrectomy in Mice using Surgical Clips
05:16

Sleeve Gastrectomy in Mice using Surgical Clips

Published on: November 14, 2020

6.7K

Related Experiment Videos

Last Updated: Jul 15, 2025

Isolation of Mesenchymal Stem Cells from Human Alveolar Periosteum and Effects of Vitamin D on Osteogenic Activity of Periosteum-derived Cells
06:47

Isolation of Mesenchymal Stem Cells from Human Alveolar Periosteum and Effects of Vitamin D on Osteogenic Activity of Periosteum-derived Cells

Published on: May 4, 2018

9.4K
Roux-en-Y Gastric Bypass Operation in Rats
07:37

Roux-en-Y Gastric Bypass Operation in Rats

Published on: June 11, 2012

23.6K
Sleeve Gastrectomy in Mice using Surgical Clips
05:16

Sleeve Gastrectomy in Mice using Surgical Clips

Published on: November 14, 2020

6.7K

Area of Science:

  • Bariatric surgery
  • Endocrinology
  • Nutritional science

Background:

  • Bariatric surgery alters gastrointestinal absorption, potentially affecting nutritional status, particularly vitamin D.
  • Understanding the impact of different bariatric procedures on vitamin D and body composition is crucial for patient management.

Purpose of the Study:

  • To compare vitamin D levels and body composition between patients undergoing Roux-en-Y gastric bypass (RYGB) and vertical sleeve gastrectomy (VSG).

Main Methods:

  • Retrospective cohort study of 120 obese patients (class II/III, aged 18-65) undergoing VSG or RYGB.
  • Collected data included demographics, time since surgery, obesity metrics, body composition (fat mass), physical activity, and food frequency.
  • Analyzed serum 25-hydroxyvitamin D (25OHD) and insulin variables.

Main Results:

  • No significant difference in body composition or post-surgical vitamin D levels between VSG and RYGB groups.
  • Significant differences observed in parathyroid hormone (PTH), total bone mineral density (BMD), and insulin variables between groups.
  • Intragroup analysis showed significant changes in body mass index (BMI) and vitamin D for VSG, and BMI for RYGB.

Conclusions:

  • Both VSG and RYGB are effective in reducing fat mass.
  • The procedures show similar outcomes regarding post-surgical vitamin D levels, with variations noted in PTH, BMD, and insulin.
  • Further research may be needed to fully elucidate long-term nutritional impacts.