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The potential of leptin to alleviate chronic heart failure through miR-27a/b-3p: A preclinical study

Jian Yan1, Jinlin Xiao1, Jian Duan1

  • 1Department of Neurosurgery, The First Affiliated Hospital of Nanchang University, 17 Yongwaizheng Street, 330006, Nanchang, China.

Asian Journal of Surgery
|September 30, 2023
PubMed
Abstract

No abstract available in PubMed .

Keywords:
Chronic heart failureLeptinmiR-27a/b-3p

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Systolic Heart Failure and Compensatory MechanismsSystolic heart failure (also termed HFrEF, Heart Failure with Reduced Ejection Fraction) is the most prevalent type of heart filure. It results in a decreased volume of blood being pumped from the ventricle. The aortic arch and carotid sinuses have baroreceptors that detect reduced blood pressure, triggering the sympathetic nervous system (SNS) to release epinephrine and norepinephrine. Initially, this response aims to boost heart rate and...
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