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Prescribing for pregnancy: inflammatory rheumatic disease
Samantha Steele1, Iona Thorne2
1Department of Obstetric Medicine, Chelsea and Westminster NHS Foundation Trust, West Middlesex University Hospital, Isleworth, UK samantha.steele6@nhs.net.
Drug and Therapeutics Bulletin
|October 1, 2023
Summary
Managing inflammatory rheumatic diseases during pregnancy is crucial. Achieving disease remission before conception and maintaining control throughout pregnancy improves outcomes for both mother and child.
Area of Science:
- Rheumatology
- Obstetrics
- Pharmacology
Background:
- Inflammatory rheumatic diseases (IRDs) pose unique challenges during pregnancy.
- Successful pregnancy outcomes depend on disease remission and control.
Purpose of the Study:
- To discuss the impact of IRDs on pregnancy and vice versa.
- To emphasize pre-pregnancy care and collaborative obstetric-rheumatology management.
- To review prescribing practices before, during, and after pregnancy.
Main Methods:
- Literature review on IRDs in pregnancy.
- Analysis of disease impact and management strategies.
- Focus on pharmacotherapy in pregnancy.
Main Results:
- Disease remission at conception is key for successful pregnancy.
- Pregnancy can influence IRD activity, and vice versa.
- Optimizing medication is essential throughout the pregnancy continuum.
Conclusions:
- Pre-pregnancy counseling and planning are vital.
- Multidisciplinary collaboration between obstetricians and rheumatologists is essential.
- Careful pharmacotherapy management is critical for safe and effective treatment.
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