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Transcranial Direct Current Stimulation for Knee Osteoarthritis: A Systematic Review and Meta-Analysis of Randomized
Jia-Man Yang1, Cong-Cong Li1, Yi Wang1
1Guangzhou University of Chinese Medicine, Guangzhou, China.
Arthritis Care & Research
|October 2, 2023
Summary
Transcranial direct current stimulation (tDCS) significantly reduces pain in knee osteoarthritis (KOA) patients. However, it showed no significant improvement in physical function, stiffness, mobility, or quality of life.
Area of Science:
- Neuroscience
- Orthopedics
- Rehabilitation Medicine
Background:
- Knee osteoarthritis (KOA) is a prevalent degenerative joint disease causing pain and functional limitation.
- Current treatments for KOA offer variable relief, necessitating exploration of novel therapeutic approaches.
- Transcranial direct current stimulation (tDCS) is an emerging non-invasive neuromodulation technique with potential applications in pain management.
Conclusions:
- Transcranial direct current stimulation (tDCS) shows significant efficacy in alleviating pain for patients with knee osteoarthritis (KOA).
- Current evidence suggests tDCS may not effectively improve physical function, stiffness, mobility, or quality of life in KOA patients.
- Further research is warranted to explore the specific mechanisms and optimal application of tDCS in KOA management, particularly regarding its effect on BDNF levels.
