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Updated: Jul 15, 2025

Imaging Denatured Collagen Strands In vivo and Ex vivo via Photo-triggered Hybridization of Caged Collagen Mimetic Peptides
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Characterization of LL37 Binding to Collagen through Peptide Modification with a Collagen-Binding Domain

Ziqi Wei1, Marsha W Rolle2, Terri A Camesano1

  • 1Department of Chemical Engineering, Worcester Polytechnic Institute, 100 Institute Road, Worcester, Massachusetts 01609, United States.

ACS Omega
|October 2, 2023
PubMed
Summary

We investigated how modified antimicrobial peptides (AMPs) bind to collagen for better wound healing dressings. The collagen-binding domain (cCBD) enhances peptide stability and retention on collagen scaffolds, suggesting improved wound care applications.

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