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Updated: Jul 15, 2025

In vivo Structural Assessments of Ocular Disease in Rodent Models using Optical Coherence Tomography
Published on: July 24, 2020
Perspective on the optics of medical imaging
1University of Wisconsin-Madison, Department of Medical Physics, Madison, Wisconsin, United States.
Significance:
Medical imaging is very commonly described as synonymous with radiological imaging, yet optical imaging devices are widely distributed throughout many medical specialties. This delocalized nature of the technology reduces visibility and dominance as a cohesive medical technology sector.
Aim:
Indicators of impact of medical optical systems were examined and compared to the radiology technology sector.
Approach:
This study included a summary of (i) physician users, (ii) global technology valuations, and (iii) NIH funding levels. Analysis focused on comparing optical and radiological technology, comparing costs, funding, and finding differences, while tabulating strengths, weaknesses, opportunities, and threats to the field of optical imaging.
Results:
The 2023 global technology revenue valuation of biomedical optical tools is $128 billion USD/year while that of radiological tools is $48 billion USD/year. A direct comparison of US NIH funding in radiology shows $8.5 billion/year, whereas optical devices are nearer to $3.6 billion USD/year. R&D investment in applications, such as endoscopy, laparoscopy, and pulse oximetry, is far below those of radiological tools when normalized by valuation.
Conclusions:
The medical optical device industry is highly fragmented but has become the largest single technology sector in medicine today. When contrasted to radiology, it appears underfunded for research, where point-of-care tools such as surgery, endoscopy, laparoscopy, ophthalmology, pulse oximetry, and monitoring have more potential for development through research investment.
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