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Updated: Jul 15, 2025
Ultrasound-based Pulse Wave Velocity Evaluation in Mice
Published on: February 14, 2017
Tissue ultrasound imaging based on wavelet correlation analysis and pulse-inversion technique
Xiaoyan Zhao1, Cuiyun Yang1, Yuchao Lyu1
1Department of Information Engineering, School of Information Science and Technology, Qingdao University of Science and Technology, Tsingtao, Shandong, China.
Background:
Pulse-inversion-based tissue harmonic imaging has been utilized for many years because it can effectively eliminate the harmonic leakage and produce low side-lobe. However, the pulse inversion method is sensitive to imaging object movements, which may result in motion artifacts. Spatial resolution and contrast were limited.
Objective:
To improve ultrasound image quality by a new pulse-inversion-based tissue harmonic imaging technique.
Methods:
Continuous wavelet transform is applied to investigate the correlation between mother wavelet and the received echoes from two opposite pulses. To get a better correlation, a novel mother wavelet named 'tissue wavelet' is designed based on the Khokhlov-Zabolotskaya- Kuznetsov (KZK) wave equation. Radio frequency data were obtained from open Ultrasonix SonixTouch imaging system. Experiments were carried on ultrasonic tissue phantom, human carotid artery and human liver.
Results:
The average improvement of lateral spatial resolution is 49.52% compared to pulse-inversion-based tissue second-harmonic Imaging (PIHI). Contrast ratio (CR) and contrast-to-noise ratio (CNR) increased by 5.55 dB and 1.40 dB over PIHI. Tissue wavelet performs better than Mexh and Morl wavelet in lateral spatial resolution, CR, and CNR.
Conclusion:
The proposed technique effectively improves the imaging quality in lateral spatial resolution, CR, and CNR.
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