Statical Association between Clinical and Histopathological Parameters for Keratinocyte Carcinomas

Area of Science:

• Dermatology
• Oncology
• Pathology

Background:

• Non-melanoma skin cancers, previously keratinocyte carcinomas (KCs), are the most prevalent tumors in Western countries.
• Understanding the incidence and risk factors is crucial for effective management.

Purpose of the Study:

• To determine the incidence of non-melanoma skin tumors.
• To investigate the relationship between histopathological risk factors and skin cancer prognosis.

Main Methods:

• Statistical analysis of clinical and histopathological aggressivity factors in 332 skin malignancy cases.
• Digital storage and comparison tests were employed for data analysis.

Main Results:

• For basal cell carcinoma (BCC), significant relationships were found between pT category and gender, tumor size, ulceration, depth of invasion, and positive resection limits.
• For squamous cell carcinoma (SCC), significant relationships were observed between pT category and tumor size, depth of invasion, and positive resection limits.

Conclusions:

• Clinical and histological analysis of skin cancer characteristics is essential for improving prognosis and therapy standards.
• Identifying specific risk factors aids in better patient management and treatment strategies for BCC and SCC.