Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Myasthenia Gravis: Diagnostic Tests01:15

Myasthenia Gravis: Diagnostic Tests

960
Myasthenia gravis is an autoimmune condition affecting neuromuscular transmission, causing generalized weakness in skeletal muscles. Initial diagnoses rely on patients' signs, symptoms, and medical history. The challenge lies in distinguishing myasthenia from other muscular dystrophies. An important diagnostic feature is the significant improvement of symptoms after administering anticholinesterase inhibitors.
The edrophonium test is a diagnostic tool for myasthenia gravis. It involves...
960
Neurogenesis and Regeneration of Nervous Tissue01:15

Neurogenesis and Regeneration of Nervous Tissue

848
In the CNS, neurogenesis, the birth of new neurons from stem cells, is limited to the hippocampus in adults. In other regions of the brain and spinal cord, neurogenesis is almost non-existent due to inhibitory influences from neuroglia, especially oligodendrocytes, and the absence of growth-stimulating cues. The myelin produced by oligodendrocytes in the CNS inhibits neuronal regeneration. Furthermore, astrocytes proliferate rapidly after neuronal damage, forming scar tissue that physically...
848

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Ultra High-Resolution Ultrasound Features of Carpal Tunnel Syndrome in Transthyretin Amyloidosis: A Cross-Sectional Study.

Muscle & nerve·2026
Same author

Spurious passage of <i>Calodium hepaticum</i> in human stools misidentified as <i>Trichuris</i> spp. infection in school-age children in Angola.

Journal of clinical microbiology·2026
Same author

Unveiling Dirofilaria Asiatica infection: first clinical insights and treatment challenges for this feline zoonotic parasitosis.

Veterinary research communications·2025
Same author

Genetic characterization of zoonotic <i>Dirofilaria asiatica</i> in Cambodian dogs through nanopore metabarcoding.

Microbiology spectrum·2025
Same author

Resistance of companion animal parasites to antiparasitic drugs.

Advances in parasitology·2025
Same author

Peripheral immune patterns enable robust cross-platform prediction of ALS onset and progression.

bioRxiv : the preprint server for biology·2025
Same journal

Isolated Cranial Tremors: A Reappraisal.

Seminars in neurology·2026
Same journal

Dystonia and Tremor.

Seminars in neurology·2026
Same journal

Pendular nystagmus and oculopalatal tremor.

Seminars in neurology·2026
Same journal

Sanjay Pandey, MBBS, MD, DNB, DM, FIAN, and Aasef Shaikh, MD, PhD.

Seminars in neurology·2026
Same journal

Tremor.

Seminars in neurology·2026
Same journal

Carotid Disease.

Seminars in neurology·2026
See all related articles

Related Experiment Video

Updated: Jul 15, 2025

A Simple Approach to Induce Experimental Autoimmune Neuritis in C57BL/6 Mice for Functional and Neuropathological Assessments
07:30

A Simple Approach to Induce Experimental Autoimmune Neuritis in C57BL/6 Mice for Functional and Neuropathological Assessments

Published on: November 9, 2017

9.4K

Neuroprognostication: Guillain-Barré Syndrome.

Rebecca Traub1, Vinay Chaudhry1

  • 1Department of Neurology, University of North Carolina, Chapel Hill, North Carolina.

Seminars in Neurology
|October 3, 2023
PubMed
Summary
This summary is machine-generated.

Guillain-Barré syndrome is an immune disorder causing nerve weakness. While treatments like IV immunoglobulin and plasma exchange are effective, some patients experience long-term fatigue and pain.

More Related Videos

Automated Gait Analysis to Assess Functional Recovery in Rodents with Peripheral Nerve or Spinal Cord Contusion Injury
06:31

Automated Gait Analysis to Assess Functional Recovery in Rodents with Peripheral Nerve or Spinal Cord Contusion Injury

Published on: October 6, 2020

6.2K
Utility of Dissociated Intrinsic Hand Muscle Atrophy in the Diagnosis of Amyotrophic Lateral Sclerosis
08:16

Utility of Dissociated Intrinsic Hand Muscle Atrophy in the Diagnosis of Amyotrophic Lateral Sclerosis

Published on: March 4, 2014

31.9K

Related Experiment Videos

Last Updated: Jul 15, 2025

A Simple Approach to Induce Experimental Autoimmune Neuritis in C57BL/6 Mice for Functional and Neuropathological Assessments
07:30

A Simple Approach to Induce Experimental Autoimmune Neuritis in C57BL/6 Mice for Functional and Neuropathological Assessments

Published on: November 9, 2017

9.4K
Automated Gait Analysis to Assess Functional Recovery in Rodents with Peripheral Nerve or Spinal Cord Contusion Injury
06:31

Automated Gait Analysis to Assess Functional Recovery in Rodents with Peripheral Nerve or Spinal Cord Contusion Injury

Published on: October 6, 2020

6.2K
Utility of Dissociated Intrinsic Hand Muscle Atrophy in the Diagnosis of Amyotrophic Lateral Sclerosis
08:16

Utility of Dissociated Intrinsic Hand Muscle Atrophy in the Diagnosis of Amyotrophic Lateral Sclerosis

Published on: March 4, 2014

31.9K

Area of Science:

  • Neurology
  • Immunology
  • Clinical Medicine

Background:

  • Guillain-Barré syndrome is an immune-mediated peripheral neuropathy.
  • It presents with rapidly progressive symmetric weakness and areflexia.
  • Albuminocytological dissociation is a key diagnostic feature.

Purpose of the Study:

  • To summarize the key characteristics, management, and outcomes of Guillain-Barré syndrome.
  • To identify prognostic factors for poor outcomes and residual symptoms.
  • To highlight critical aspects of patient monitoring and care.

Main Methods:

  • Review of clinical presentation and diagnostic criteria.
  • Analysis of treatment efficacy for intravenous immunoglobulin and plasma exchange.
  • Identification of risk factors for disease severity, mortality, and long-term sequelae.

Main Results:

  • Most patients stabilize within two weeks, but severity varies, with 20% needing mechanical ventilation.
  • Intravenous immunoglobulin and plasma exchange show comparable effectiveness.
  • Poor outcomes are associated with older age, preceding diarrhea, and lower MRC scores.
  • Mortality ranges from 3-7%, with advanced age and disease severity as risk factors.
  • Residual symptoms include pain, weakness, and fatigue, linked to axonal loss and illness severity.

Conclusions:

  • Guillain-Barré syndrome requires comprehensive management including monitoring, respiratory support, and rehabilitation.
  • Prognosis is influenced by patient age, preceding illness, and initial disease severity.
  • Long-term sequelae are common and associated with specific clinical and pathological factors.