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Updated: Jul 22, 2026

Amide Coupling Reaction for the Synthesis of Bispyridine-based Ligands and Their Complexation to Platinum as Dinuclear Anticancer Agents
Published on: May 28, 2014
Trinuclear rhenium(I)-based metallocages as anticancer agents towards human cervical cancer cells
Moon Kedia1, Sajmina Khatun2, Upasana Phukon1
1School of Chemistry, University of Hyderabad, Hyderabad-500 046, India. msathi@uohyd.ac.in.
Abstract:
The first examples of spherical-shaped trinuclear rhenium(I) organometallic cages displaying cytotoxic, antimetastatic, antiproliferative and DNA-damaging behavior towards a human cervical (HeLa) cancer cell line are reported. The compact design of the metallocages facilitates their interactions with biosystems leading to comparable efficiency to that of the commonly used anticancer drug cisplatin.
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