Related Experiment Video
Updated: Jul 15, 2025

Infant Auditory Processing and Event-related Brain Oscillations
Published on: July 1, 2015
Corpus callosum abnormalities at term-equivalent age are associated with language development at two years corrected
Katsuaki Kojima1,2, Julia E Kline1, Mekibib Altaye1,2,3
1Neurodevelopmental Disorders Prevention Center, Perinatal Institute, Cincinnati Children's Hospital Medical Center, 3333 Burnet Avenue, Cincinnati, OH 45229-3039.
Abstract:
We studied the impact of microstructural abnormalities in the corpus callosum on language development in 348 infants born very prematurely. We discovered that the fractional anisotropy of the corpus callosum anterior midbody was a significant predictor of standardized language scores at two years, independent of clinical and social risk factors.
Related Concept Videos
Language Development
The critical period for language acquisition suggests that the ability to acquire language is at its peak early in life. As people age, this proficiency decreases. Language development begins very...
Language and Cognition
Cerebral Hemispheres
Higher Mental Functions of the Brain: Language
Language formation and comprehension take place in the dominant hemisphere. The dominant hemisphere is responsible for understanding the meaning of spoken, written, or sign language, as well as the ability to communicate. For most people, the left hemisphere is the dominant one. The right hemisphere, then, gives tone and emotional context to the...
Lateralization

