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[Dementia : current guidelines for clinical management]
Mohamed Eshmawey1, Salem Boudouh1, Paul G Unschuld1
1Service de psychiatrie gériatrique, Département de psychiarie, Hôpital de Belle-Idée, Hôpitaux universitaires de Genève, Chemin du Petit Bel-Air, 1226 Thônex.
Revue Medicale Suisse
|October 4, 2023
Summary
Dementia describes cognitive decline interfering with daily life, often caused by Alzheimer's disease (AD). New monoclonal antibody therapies show promise for soon modulating AD disease progression.
Area of Science:
- Neurology
- Geriatrics
- Pharmacology
Context:
- Dementia is a syndrome characterized by cognitive decline impacting daily functioning.
- Alzheimer's disease (AD) is the most common cause, but other conditions contribute to dementia in older adults.
- Current management focuses on symptom relief and daily life support.
Purpose:
- To provide an overview of dementia as a syndrome.
- To discuss current treatment approaches for dementia symptoms.
- To highlight emerging therapeutic strategies for Alzheimer's disease.
Summary:
- Dementia encompasses a range of symptoms causing significant cognitive decline and functional impairment.
- While Alzheimer's disease is a primary cause, dementia is a syndrome with diverse underlying pathologies.
- Treatment strategies address cognitive deficits, behavioral issues, sleep disturbances, and daily living challenges.
Impact:
- Effective dementia management requires a personalized approach to address multifaceted patient needs.
- Emerging monoclonal antibody therapies offer potential for disease-modifying treatments in Alzheimer's disease.
- Advancements in neurobiological understanding may lead to treatments that can alter disease progression.
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