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Related Concept Videos

Cancer Prevention02:59

Cancer Prevention

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Several factors can increase the risk of cancer in an individual. About 50% of cancer cases can be prevented by adopting a healthy lifestyle, regular exercise, eating healthy, and following a modest cancer prevention diet. Epidemiological studies have consistently shown that populations with vegetable and fruit-rich diets have reduced the incidence of cancer. On the other hand, populations who have a diet rich in animal fat, red meat, junk food, or high calories are predisposed to cancer.
Some...
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Cancer Therapies02:49

Cancer Therapies

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Cancer therapies are various modes of treatment, such as surgery, radiation therapy, and chemotherapy that are administered to cancer patients.
However, cancer treatments can pose several challenges, as therapies used to kill cancer cells are generally also toxic to normal cells. Moreover, cancer cells mutate rapidly and can develop resistance to chemical agents or radiation therapy. Besides, all types of cancer cells may not respond to the same therapy. Some cancer cells respond to one...
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Treatment Resistant Cancers02:56

Treatment Resistant Cancers

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Cancer is the second leading cause of death in the United States. A cancer cell is genetically unstable and hence can mutate faster. They can also modify their microenvironment and escape immune surveillance. The difficulties in treating cancer are further compounded by the emergence of rapid resistance to anticancer drugs. The most common ways to attain resistance in cancer cells include alteration in drug transport and metabolism, modification of drug target, elevated DNA damage response, or...
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Cognitive Development During Adulthood01:30

Cognitive Development During Adulthood

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Cognitive development continues throughout adulthood, undergoing significant shifts across early, middle, and late stages. Individual transition occurs from adolescent idealism to pragmatic and adaptable thinking in early adulthood. During this period, individuals learn to integrate personal beliefs with the recognition that other perspectives are equally valid. Exposure to the complexities of modern society, diverse experiences, and higher education contribute to this adaptive thought process,...
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Targeted Cancer Therapies02:57

Targeted Cancer Therapies

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The targeted cancer therapies, also known as “molecular targeted therapies,” take advantage of the molecular and genetic differences between the cancer cells and the normal cells. It needs a thorough understanding of the cancer cells to develop drugs that can target specific molecular aspects that drive the growth, progression, and spread of cancer cells without affecting the growth and survival of other normal cells in the body.
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Adaptive Mechanisms in Cancer Cells02:53

Adaptive Mechanisms in Cancer Cells

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Cancer cells accumulate genetic changes at an abnormally rapid rate due to the defects in the DNA repair mechanisms. From an evolutionary perspective, such genetic instability is advantageous for cancer development. Mutant cell lines accumulate a series of beneficial mutations that contribute to their progression into cancer.
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Updated: Jul 15, 2025

Quantifying Cognitive Decrements Caused by Cranial Radiotherapy
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Interventions to Address Cancer-Related Cognitive Impairment (2018-2022).

Claudine Campbell1, Katie M Polo2, Anne Fleischer3

  • 1Claudine Campbell, OTD, OTR/L, CLT, is Lead Occupational Therapist, Memorial Sloan Kettering Cancer Center.

The American Journal of Occupational Therapy : Official Publication of the American Occupational Therapy Association
|October 4, 2023
PubMed
Summary
This summary is machine-generated.

This review summarizes evidence on cancer-related cognitive impairment in adults. Findings address cognitive changes and challenges faced by cancer survivors.

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Area of Science:

  • Occupational therapy
  • Evidence-based practice
  • Cancer survivorship

Background:

  • Cancer-related cognitive impairment, often termed 'chemo-brain', affects adults during and after cancer treatment.
  • Cognitive changes can significantly impact daily functioning and quality of life for cancer survivors.
  • Understanding this impairment is crucial for developing effective occupational therapy interventions.

Conclusions:

  • Cancer-related cognitive impairment is a significant issue for adult survivors, impacting their occupational performance.
  • Occupational therapy practitioners can utilize this evidence to support individuals experiencing cognitive challenges.
  • Further research is needed to refine interventions and improve long-term outcomes for cancer survivors.