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Related Concept Videos

Glassware Calibration01:11

Glassware Calibration

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Accurate calibration of glassware, such as volumetric flasks, pipettes, and burettes, is essential to ensure accurate measurements in the analytical laboratory. Calibration helps maintain consistency across measurements and prevents errors arising from inaccurate volumes.
Volumetric flasks: Volumetric flasks are designed to prepare aqueous solutions of precise volumes accurately with a calibration line on the neck. To calibrate a volumetric flask, it is important to fill it with distilled...
257

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An Open Source Technology Platform to Manufacture Hydrogel-Based 3D Culture Models in an Automated and Standardized Fashion
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Open source scientific bottle roller.

Maryam Mottaghi1, Yuntian Bai1, Apoorv Kulkarni2

  • 1Department of Mechanical and Materials Engineering, Western University, 1151 Richmond St., London, Ontario N6A 5B9 Canada.

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|October 5, 2023
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Summary
This summary is machine-generated.

This study presents an affordable open-source bottle roller, costing only $150. This 3D-printable device offers enhanced capabilities and accessibility for laboratory automation, significantly reducing costs compared to commercial options.

Keywords:
3D printingBottle rollerBottle rollingChemical mixingOpen hardwareScientific hardware

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Area of Science:

  • Biotechnology
  • Laboratory Automation
  • Open Source Hardware

Background:

  • High cost of proprietary bottle rollers limits accessibility in research.
  • Need for affordable, customizable laboratory automation solutions.

Purpose of the Study:

  • To design and fabricate an open-source bottle roller using 3D printing and accessible components.
  • To provide a cost-effective and robust alternative to commercial bottle rolling systems.

Main Methods:

  • Utilized distributed digital manufacturing with 3D-printed parts and commercial components.
  • Designed for compatibility with low-profile incubators and elevated temperatures.
  • Tested rotational speed range (1-200 RPM), capacity (1.2 kg, 12x100 mL bottles), and long-term stability.

Main Results:

  • Fabrication cost of $210 CAD (approx. $150 USD), an 86% cost reduction.
  • Demonstrated robustness, adaptability, and compatibility with standard laboratory equipment.
  • Achieved reliable operation for extended periods (days) at various speeds and temperatures (up to 50°C).

Conclusions:

  • The open-source bottle roller offers a significantly cheaper, more capable, and adaptable solution for laboratory automation.
  • This design democratizes access to essential lab equipment through digital manufacturing.
  • Further development will focus on cost reduction and increased fabrication flexibility.