Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Myasthenia Gravis: Overview and Treatment01:20

Myasthenia Gravis: Overview and Treatment

1.5K
Myasthenia gravis is a neuromuscular transmission disorder characterized by weakness and increased fatigability of skeletal muscles. It is an autoimmune disease affecting approximately one in 2000 people, where antibodies against the α1 subunit of nicotinic acetylcholine receptors are produced.
These antibodies interfere with the function of the nicotinic receptors in three ways: by binding to the receptor and disrupting acetylcholine binding; by causing cross-linking of receptors which...
1.5K
Myasthenia Gravis: Diagnostic Tests01:15

Myasthenia Gravis: Diagnostic Tests

937
Myasthenia gravis is an autoimmune condition affecting neuromuscular transmission, causing generalized weakness in skeletal muscles. Initial diagnoses rely on patients' signs, symptoms, and medical history. The challenge lies in distinguishing myasthenia from other muscular dystrophies. An important diagnostic feature is the significant improvement of symptoms after administering anticholinesterase inhibitors.
The edrophonium test is a diagnostic tool for myasthenia gravis. It involves...
937
Disorders of the Skeletal Muscle01:28

Disorders of the Skeletal Muscle

976
The clinical conditions affecting the skeletal muscle tissue are broadly categorized as musculoskeletal and neuromuscular disorders.
Musculoskeletal disorders
Musculoskeletal disorders involve injuries and conditions affecting the skeletal muscles and associated connective tissues. These disorders can arise from acute biomechanical stresses or chronic overuse and can occur across different age groups. Common injuries include sprains, fractures, and muscular strains, often resulting from...
976
Accessory Structures of the Eye01:17

Accessory Structures of the Eye

1.6K
Optical perception, or vision, is an extraordinary sense dependent on converting light signals received via the ocular organs. These organs, known as eyes, are securely positioned within the bony cavities of the skull, called orbits. The orbits serve a dual purpose: a protective shield for the ocular globes and a stable attachment point for the soft ocular tissues. The eye's external protective mechanisms include the eyelids, which are edged with lashes that act as a barrier against foreign...
1.6K
Muscles of the Eye01:20

Muscles of the Eye

1.4K
The muscles of the eye are sophisticated structures that control eye movement and focus, allowing for the precise and rapid adjustments necessary for vision. The human eye is controlled by ten muscles — six extraocular muscles, three intraocular muscles, and one primary eyelid retractor muscle.
Extraocular Muscles
The six extraocular muscles surround the eyeball and control its movements. They are responsible for a wide range of eye motions, including looking up, down, left, right, and...
1.4K
Direct-Acting Cholinergic Agonists: Therapeutic Uses01:11

Direct-Acting Cholinergic Agonists: Therapeutic Uses

775
Direct-acting cholinergic agonists have many therapeutic uses in various medical fields. Choline esters, including acetylcholine, have limited clinical utility due to their non-selectivity and short duration of action. Still, acetylcholine and carbachol are applied topically during ophthalmologic surgery to induce miosis. Pilocarpine, a muscarinic and ganglionic stimulator, effectively treats open-angle glaucoma and alleviates xerostomia and dry mouth caused by radiotherapy or Sjögren...
775

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Botulism Sequelae: A Systematic Review.

Open forum infectious diseases·2026
Same author

[Modern ideas about the relationship between fibromyalgia and mental disorders].

Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova·2023
Same author

[Transcranial magnetic stimulation in the treatment of depressive disorder in Parkinson's disease].

Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova·2022
Same author

[Neuralgic amyotrophy].

Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova·2022
Same author

[Myasthenia gravis and muscle atrophy].

Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova·2021

Related Experiment Video

Updated: Jul 14, 2025

Author Spotlight: Ex Vivo OCT-Based Multimodal Imaging of Human Donor Eyes for Research into Age-Related Macular Degeneration
10:14

Author Spotlight: Ex Vivo OCT-Based Multimodal Imaging of Human Donor Eyes for Research into Age-Related Macular Degeneration

Published on: May 26, 2023

3.2K

[Ocular myasthenia gravis].

A G Sanadze1,2,3, D V Sidnev2, D A Tumurov1,2,3

  • 1Buyanov City Clinical Hospital, Moscow, Russia.

Zhurnal Nevrologii I Psikhiatrii Imeni S.S. Korsakova
|October 5, 2023
PubMed
Summary

Diagnosing ocular myasthenia gravis (OMG) is challenging due to limited lab test effectiveness. This review emphasizes clinical signs and modern treatments for OMG, improving patient outcomes.

Keywords:
diplopiaextraocular musclesmyasthenia gravisptosis

More Related Videos

Induction of Ocular Surface Inflammation and Collection of Involved Tissues
06:38

Induction of Ocular Surface Inflammation and Collection of Involved Tissues

Published on: August 4, 2022

2.3K
A Magnetic Microbead Occlusion Model to Induce Ocular Hypertension-Dependent Glaucoma in Mice
09:26

A Magnetic Microbead Occlusion Model to Induce Ocular Hypertension-Dependent Glaucoma in Mice

Published on: March 23, 2016

19.5K

Related Experiment Videos

Last Updated: Jul 14, 2025

Author Spotlight: Ex Vivo OCT-Based Multimodal Imaging of Human Donor Eyes for Research into Age-Related Macular Degeneration
10:14

Author Spotlight: Ex Vivo OCT-Based Multimodal Imaging of Human Donor Eyes for Research into Age-Related Macular Degeneration

Published on: May 26, 2023

3.2K
Induction of Ocular Surface Inflammation and Collection of Involved Tissues
06:38

Induction of Ocular Surface Inflammation and Collection of Involved Tissues

Published on: August 4, 2022

2.3K
A Magnetic Microbead Occlusion Model to Induce Ocular Hypertension-Dependent Glaucoma in Mice
09:26

A Magnetic Microbead Occlusion Model to Induce Ocular Hypertension-Dependent Glaucoma in Mice

Published on: March 23, 2016

19.5K

Area of Science:

  • Neurology
  • Ophthalmology

Context:

  • Ocular myasthenia gravis (OMG) presents diagnostic challenges.
  • Limited efficacy of current laboratory and electromyographic methods for OMG diagnosis.
  • Generalized myasthenia gravis frequently manifests with external ophthalmoplegia and ptosis.

Purpose:

  • To highlight diagnostic and differential diagnostic features of ocular myasthenia gravis.
  • To present data on the clinical course and presentation of ocular myasthenia gravis.
  • To discuss modern treatment approaches for ocular myasthenia gravis.

Summary:

  • The diagnosis of ocular myasthenia gravis (OMG) remains difficult despite advances in synaptic pathology.
  • Effective diagnosis relies on careful analysis of patient history and clinical manifestations.
  • The article reviews current treatment strategies and presents case studies.

Impact:

  • Improved diagnostic accuracy for ocular myasthenia gravis.
  • Enhanced understanding of clinical presentations and disease course.
  • Guidance on modern therapeutic interventions for ocular myasthenia gravis.