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Doppler Optical Coherence Tomography of Retinal Circulation
Published on: September 18, 2012
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Needle guidance with Doppler-tracked polarization-sensitive optical coherence tomography
Danielle J Harper1,2, Yongjoo Kim1,2, Alejandra Gómez-Ramírez1,3
1Massachusetts General Hospital, Wellman Center for Photomedicine, Boston, Massachusetts, United States.
Journal of Biomedical Optics
|October 6, 2023
Summary
Polarization-sensitive optical coherence tomography (PS OCT) enhances tissue discrimination in unscanned needle probes. This advancement improves real-time guidance for medical procedures, increasing clinical utility.
Area of Science:
- Biomedical optics
- Medical imaging
- Surgical navigation
Background:
- Optical coherence tomography (OCT) integrated into needle probes offers real-time guidance.
- Unscanned OCT needle probes, while simple, face challenges in differentiating target tissues.
Purpose of the Study:
- To investigate the use of polarization-sensitive (PS) methods to improve signal interpretability in unscanned OCT needle probes.
- To enhance the clinical applicability of OCT-guided needle interventions.
Main Methods:
- Broadband 1310 nm laser light delivered via fiber-embedded needle.
- Combined PS OCT fringes with Doppler tracking for tissue birefringence visualization.
- Tested on salmon, shrimp, and ex vivo porcine spine for epidural guidance simulation.
Main Results:
- PS OCT imaging successfully identified skin, subcutaneous tissue, ligament, and epidural spaces in porcine spine.
- Doppler-tracked PS OCT provided enhanced signal interpretability compared to structural OCT.
- Demonstrated feasibility for epidural needle insertion guidance.
Conclusions:
- PS imaging significantly improves signal interpretability in unscanned OCT needle probes.
- This technique holds potential to advance the clinical utility of OCT-guided needle interventions.
- Enhances navigation and tissue differentiation in minimally invasive procedures.
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