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Epidemiology of systemic vasculitis
Yesim Ozguler1, Sinem Nihal Esatoglu, Gulen Hatemi
1Division of Rheumatology, Department of Internal Medicine, Cerrahpaşa Medical Faculty, Istanbul University-Cerrahpaşa, Istanbul, Turkey.
Current Opinion in Rheumatology
|October 6, 2023
Summary
Recent studies reveal vasculitis, including giant cell arteritis and Behçet syndrome, are more common than previously thought. Standardized criteria are needed for accurate global epidemiology of these rare diseases.
Area of Science:
- Rheumatology
- Epidemiology
Background:
- Geographic variations in vasculitis epidemiology are significant, with limited data from certain regions.
- Increased disease recognition and improved diagnostics may influence observed epidemiological trends.
- Systemic vasculitis encompasses rare but impactful inflammatory conditions affecting blood vessels.
Approach:
- This review synthesizes recent epidemiological data on systemic vasculitis.
- It highlights emerging findings on the prevalence and incidence of specific vasculitic diseases.
- The review addresses challenges in comparing data across different geographical areas and time periods.
Key Points:
- Giant cell arteritis, Takayasu arteritis, and Behçet syndrome appear more prevalent than previously estimated in underrepresented regions.
- The coronavirus disease 2019 pandemic's impact on Kawasaki disease incidence suggests links with respiratory pathogens.
- Inconsistent classification criteria for antineutophil cytoplasmic antibody (ANCA)-associated vasculitis hinder accurate international and temporal comparisons.
Conclusions:
- Recent research underscores the evolving epidemiology of vasculitides globally.
- Standardization of research methodologies and disease definitions is crucial for reliable epidemiological comparisons.
- Further research is needed to address data gaps and refine our understanding of vasculitis distribution and trends.
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