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Multifunctional MXene-Based Bioactive Materials for Integrated Regeneration Therapy.

Junping Ma¹, Long Zhang^1,2, Bo Lei^1,3

¹Frontier Institute of Science and Technology, Xi'an Jiaotong University, Xi'an 710000, China.

|October 7, 2023

Summary

This summary is machine-generated.

MXenes, advanced nanomaterials, show promise for tissue regeneration and disease treatment. This review explores their use in combined regeneration-therapy for cancer, infection, and inflammation, highlighting potential and challenges.

Keywords:

MXenes bioactive materials bone regeneration cancer therapy infection therapy inflammation therapy multifunctional properties tissue engineering wound healing

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Area of Science:

Biomedical Engineering
Materials Science
Nanotechnology

Background:

Tissue defects from diseases like cancer, infection, and inflammation pose clinical challenges.
Multifunctional bioactive materials are crucial for overcoming impaired tissue regeneration.
MXenes, as 2D nanomaterials, offer unique properties for biomedical applications.

Purpose of the Study:

To review recent advances in MXene properties and their applications in integrated tissue regeneration and therapy.
To explore MXene-based biomaterials for combined tissue regeneration with tumor, infection, and inflammation therapy.
To discuss current challenges and future perspectives for MXene-based regeneration-therapy.

Main Methods:

Literature review of MXene properties and applications in tissue engineering and therapy.
Analysis of MXene-based biomaterials for combined regeneration-therapy strategies.
Discussion of mechanisms, biosafety, and targeting capacity of MXenes.

Main Results:

MXenes exhibit multifunctional physicochemical properties suitable for nanoplatforms.
MXene-based biomaterials show potential in tissue regeneration combined with cancer, infection, and inflammation therapy.
Applications include photothermal therapy, cell behavior regulation, and drug/gene delivery.

Conclusions:

MXene-based biomaterials hold significant promise for integrated tissue regeneration and disease treatment.
Further research is needed to understand bioactive mechanisms and ensure long-term biosafety.
Improving targeting therapy capacity is essential for clinical translation of MXene applications.