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Post-operative rigidity after fentanyl administration.

F Bonnet, F Kergrohen, J E Lafosse

    European Journal of Anaesthesiology
    |September 1, 1986
    PubMed
    Summary
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    A moderate dose of fentanyl caused severe chest wall rigidity and respiratory failure in an elderly patient post-surgery. Naloxone successfully reversed this opioid-induced complication, highlighting the importance of prompt recognition and treatment.

    Area of Science:

    • Anesthesiology
    • Critical Care Medicine
    • Pharmacology

    Background:

    • Post-operative respiratory complications can significantly impact patient outcomes.
    • Opioid analgesics, such as fentanyl, are commonly used for pain management but carry risks.
    • Elderly patients may be more susceptible to adverse drug reactions.

    Observation:

    • A case report details an elderly patient experiencing thoraco-abdominal rigidity post-operatively.
    • The patient received a moderate dose of fentanyl for pain management.
    • This rigidity led to respiratory failure.

    Findings:

    • Fentanyl administration, even at moderate doses, can precipitate severe chest wall rigidity.
    • Respiratory failure is a critical complication associated with this phenomenon.

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  • Naloxone effectively antagonized the effects of fentanyl, reversing the rigidity and restoring respiratory function.

    • Implications:

    • This case underscores the potential for serious adverse events with fentanyl use in the elderly.
    • Awareness of fentanyl-induced chest wall rigidity is crucial for anesthesiologists and critical care physicians.
    • Prompt administration of naloxone is vital for managing this potentially life-threatening complication.