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An Orthotopic Bladder Tumor Model and the Evaluation of Intravesical saRNA Treatment
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[Adult orbital tumors].

A Ducasse1, J C Merol1, F Bonnet1

  • 1Hôpital Robert-Debré, CHRU de Reims, avenue du M.L.-Koenig, 51092 Reims, France.

Journal Francais D'Ophtalmologie
|March 28, 2016
PubMed
Summary
This summary is machine-generated.

Orbital tumors are common and can be benign or malignant, originating from various orbital tissues. Diagnosis involves clinical signs, imaging, and biopsy, guiding multidisciplinary treatment strategies.

Keywords:
Imagerie orbitaireImaging of the orbitOrbital compartment syndromeOrbital tumorsOrbitotomiesSyndrome orbitaireTumeurs de l’orbite

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Area of Science:

  • Ophthalmology
  • Oncology
  • Radiology

Background:

  • Orbital tumors represent a frequent and challenging pathology.
  • They encompass a wide range of benign and malignant neoplasms arising from diverse orbital tissues.
  • Common benign types include meningiomas and cavernous hemangiomas; malignant types include lymphomas, metastases, ENT tumors, and lacrimal gland tumors in adults.

Purpose of the Study:

  • To summarize the diagnostic and therapeutic approaches for orbital tumors.
  • To highlight the importance of integrating clinical, imaging, and histological data for effective management.

Main Methods:

  • Clinical evaluation of nonspecific signs such as proptosis, oculomotor disturbances, and pain.
  • Multimodal imaging techniques including CT, MRI, and color Doppler ultrasound to delineate tumor characteristics.
  • Histopathological confirmation through biopsy and cytopathologic examination.

Main Results:

  • Imaging modalities effectively visualize tumor location, extent, and potential metastases.
  • Biopsy and subsequent analysis are crucial for definitive tumor classification (benign vs. malignant).
  • A multidisciplinary tumor conference approach guides treatment decisions.

Conclusions:

  • Diagnosis relies on a triad of clinical presentation, imaging findings, and histological confirmation.
  • Surgical intervention is a primary treatment modality, often complemented by radiation therapy and chemotherapy.
  • Effective management necessitates a comprehensive, multidisciplinary strategy for orbital neoplasms.